グリチルリチン・グリシン・L-システインの薬剤学的研究

概要

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Analyis was carried out on 6 brands of commercial injectable preparations combining glycyrrhizin, glycine and L-cysteine. In assay, glycyrrhizin was measured by spectrophotometry, glycine by titrimetry and L-cysteine by colorimetry. The particles in size of 2-60μ were divided into 6 grades and their number was measured. Molecular structure of the preparations was studied by Laser Raman method. Results are as follows : 1) There was no significant difference in contents of glycrrhizin and glycine among the brands. 2) Remarkable shortage of L-cysteine was observed in 2 brands. 3) Significant differences in particle size were observed among the brands. 4) One of the brands showed a large signal around 1000cm^<-1> in Laser Raman spectrum.
日本医療薬学会の論文
1979-08-20