Legionella pneumophilaに対するドライハーブ抽出液の抗菌作用

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The use of dried herbs has frequently been incorporated into daily life in Japan in recent years. The antibacterial activity of dried herbs on Legionella pneumophila, which has been attracting attention as an emerging infectious disease, was investigated, and the following were obtained. 1) The antibacterial activity of extract solutions of 28 dried herbs on L.pneumophila was investigated by the disc method, and zone inhibition of the bacteria was observed with 22 herbs (78.6%) including raspberry leaf, common sage, lemon balm, and peppermint, showing an antibacterial activity of herbs on L.pneumophila. Herbs of the perilla family in particular had a strong activity. 2) Bactericidal experiments were performed with various concentrations of the herb extracts. The herbs had a bactericidal effect on L.pneumophila, and the activity was concentration dependent. Among the herbs with a 100% bactericidal rate, the maximal dilution factor was ≧16-fold that of savory and hibiscus extracts, and the second highest was 8-fold that of common thyme extract. 3) Time-course changes in the bacterial count of L.pneumophila were measured in the extract solutions of peppermint, common sage, and common thyme of the perilla family, which had strong antibacterial activity. In all these herbs, the inoculated bacterial count of 10^6 CFU/ml became undetectable after three to 12 hours. Therefore, it was shown that although the action is not immediate, herbs have a bactericidal activity on L.pneumophila.
麻布大学の論文

Legionella pneumophilaに対するドライハーブ抽出液の抗菌作用

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