<原著>口腔前癌病変,扁平上皮癌における血液型H物質の検討(予報)

概要

論文の詳細を見る
The distribution of blood group substance H in oral precancerous lesions and squamous cell carcinomas was studied. The Ulex europeus agglutinin I was used as a marker of blood group substance H in the immunoperoxidase method. Formalin fixed and paraffin embedded tissues were employed. The cell membranes of the spinous layer stained positively in normal oral mucosa, whereas the basal cells reacted negatively. Both the spinous cells and basal cells in the dysplastic epithelium in a oral premalignant lesion showed a positive reaction. Blood group substance H was present in all of the squamous cell carcinomas. The staining intensity in cancerous lesions showed a considerable variation. The present finding suggests that the difference of distribution of blood group substance H between normal squamous epithelium and dysplastic epithelium is a valuable marker for the initial change of malignant transformation in oral mucosa.
北海道医療大学の論文
1983-12-31