<原著>各種薬効別薬剤の心筋梗塞2次予防効果

概要

論文の詳細を見る
To examine the efficacy of various drugs to prevent recurrent myocardial infarction, a study was conducted on 1,634 cases with myocardial infarction, who were hospitalized or treated at the out-patient clinic between January 1986 and October 1990. Drugs studied were calcium antagonists, nitrates, antiplatelet agents, beta-blockers, warfarin and cholesterol lowering drugs. The primary endpoint was reinfarction or sudden death. One hundred and seven cases had reinfarction and there were 9 cases with sudden death. The cardiac events were significantly reduced in patients treated with antiplatelet agents among 6 drugs. There were 38 cardiac events in 906 cases (4.2%) in patients treated with antiplatelet agents, while 53 cardiac events in 715 cases (7.4%) in non-treated groups. We consider that the prevention of coronary thrombus formation by antiplatelet agents was effective for secondary prevention of myocardial infarction.
近畿大学の論文
1992-03-25