<原著>実験的甲状腺炎における自己反応細胞 : I. Plaque Forming Cell の検索

概要

論文の詳細を見る
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。It was demonstrated that the subcutaneous (or footpads) administration of thyroid extracts with various kinds of adjuvants caused the production of thyroid-specific antibodies in guinea pigs and the development of extensive lymphocytic infiltration in the thyroid gland. The skin reaction against thyroglobulin of the treated animals was strongly positive 2 weeks after the treatment, while the titre of humoral antibodies remained low. The titres in anti-thyroglobulin antibodies shown by passive haemagglutination became higher in the more advanced stages (4 weeks). In these cases, the enumeration of plaque forming cells producing anti-thyroglobulin antibodies in the spleen, lymph nodes and thyroid glands were carried out, and no plaque forming cells were shown in these organs.
京都大学の論文
1973-03-31