Undifferentiated Sarcoma of the Salivary Gland in a Mongolian Gerbil (Meriones unguiculatus)
スポンサーリンク
概要
- 論文の詳細を見る
A subcutaneous mass was found in the lower ventral neck region of a 55-week-old male Mongolian gerbil (Meriones unguiculatus). Histopathologically, the mass involved salivary glands and featured diffuse proliferation of pleomorphic neoplastic cells with large necrotic foci. The lesion was well demarcated from the surrounding tissue, although invasive growth to fibrous septa was occasionally observed. The neoplastic cells were mainly arranged in irregular sheets with severe cellular atypia, round to oval nuclei and varying amounts of eosinophilic cytoplasm. Mitotic figures and multinucleated giant cells were frequent. Immunohistochemical analysis revealed that the neoplastic cells were strongly positive for vimentin and S-100 and negative for NSE, cytokeratin, α-SMA, c-kit, factor VIII, CD34, α-1-antitrypsin, lysozyme and MSR-A. Based on the results, the mass was diagnosed as an undifferentiated sarcoma of the salivary gland. To the best of our knowledge, this is the first report of such a tumor in Mongolian gerbils.
- 日本毒性病理学会の論文
- 2011-09-01
著者
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Takami Shigeaki
Division of Pathology, National Institute of Health Sciences
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Cho Young-Man
Division of Pathology, National Institute of Health Sciences
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Cho Young-man
Division Of Pathology National Institute Of Health Sciences
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Cho Young-man
国立医薬品食品衛生研究所 病理部
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Tsukamoto Tetsuya
Division Of Oncological Pathology Aichi Cancer Center Research Institute
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高岡 雅哉
Medicinal Safety Research Laboratories Daiichi-sankyo Co. Ltd.
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Nishikawa A
Div. Of Pathology National Inst. Of Health Sciences
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Nishikawa Akiyoshi
Division Of Pathology Biology Safety Research Center National Institute Of Health Sciences
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Nishikawa A
National Inst. Health Sci. Tokyo Jpn
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Nishikawa A
National Institute Of Health Science Osaka Branch National Institute Of Health Sciences
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Makino Toshihiko
Medicinal Safety Research Laboratories Daiichi Sankyo Co. Ltd.:department Of Veterinary Pathology Gr
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Tsukamoto Takahisa
First Department Of Oral And Maxillofacial Surgery School Of Dentistry
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立松 正衞
Aichi Cancer Center Research Institute
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Takami Shigeaki
Division Of Pathology National Institute Of Health Sciences
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Takasu Shinji
Division Of Oncological Pathology Aichi Cancer Center Research Institute
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Toyoda Takeshi
Division Of Oncological Pathology Aichi Cancer Center Research Institute
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Toyoda Takeshi
Division Of Materials Science And Engineering Graduate School Of Engineering Hokkaido University
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Tatematsu M
Department Of Endoscopy Aichi Cancer Center Hospital
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Tsukamoto T
Department Of Public Health Osaka City University Graduate School Of Medicine
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Onami Saeko
Division of Pathology, National Institute of Health Sciences
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Shi Liang
Production and Technology Center, Mitsui Chemicals Inc.
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Saito Ayumi
Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine
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Matsuo Saori
Division of Pathology, National Institute of Health Sciences
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Tatematsu Masae
Japan Bioassay Research Center
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Makita Takashi
Dept. Vet. Anat. Yamaguchi Univ.
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Nishikawa Akiyoshi
Division Of Pathology Nihs
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Maejima Takanori
Medicinal Safety Research Laboratories Sankyo Co. Ltd.
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Ogawa Kumiko
Division Of Pathology National Institute Of Health Sciences
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Shi Liang
Production And Technology Center Mitsui Chemicals Inc.
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Matsuo Saori
Division Of Pathology National Institute Of Health Sciences
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Onami Saeko
Division Of Pathology National Institute Of Health Sciences
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TOGE TETSUYA
Division of Oncological Pathology, Aichi Cancer Center Research Institute
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