Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography May Predict the Outcome in Patients With Asymptomatic Mild Stenosis of Internal Carotid Artery
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概要
- 論文の詳細を見る
A 47-year-old male presented with asymptomatic mild (45%) internal carotid artery (ICA) stenosis associated with familial hypercholesterolemia. Fluorine-18-fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) showed that the carotid plaque had high uptake of [18F]FDG on the initial scan. He was treated with antiplatelet agent, but subsequently developed retinal artery occlusion on the ipsilateral side. The patient safely underwent carotid endarterectomy (CEA). Histological examination revealed that the plaque was rich in lipids and activated macrophages. Previous large randomized clinical trials have clarified that CEA is an effective therapeutic option to reduce the risk for subsequent ischemic stroke in patients with severe (more than 70%) ICA stenosis. The case strongly suggests that [18F]FDG PET may be a useful modality to identify inflamed and/or vulnerable carotid plaque and may be useful to predict the risk for subsequent ischemic stroke even in patients with mild to moderate ICA stenosis (less than 70%).
- 2011-10-15
著者
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中山 若樹
北海道大学 神経外科
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Nakayama Naoki
Department Of Neurosurgery Hokkaido University Graduate School Of Medicine
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中山 若樹
北海道大学医学部付属病院脳神経外科
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中山 若樹
札幌麻生脳神経外科病院
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Tamaki Nagara
台湾
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Nakata Tomoaki
札幌医科大学 医学部
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Shiga Tohru
Department Of Nuclear Medicine Hokkaido University Graduate School Of Medicine
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Nakata Tomoaki
Second Department Of Internal Medicine Sapporo Medicine University
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Nakayama Naoki
Department Of Neurosurgery Kushiro Rousai Hospital
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Nakayama Naoki
Department Of Neurosurgery Hokkaido University
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Tamaki Nagara
Hokkaido University School Of Medicine Department Of Tracer Kinetics And Department Of Nuclear Medic
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Hirata Kenji
Department Of Nuclear Medicine Hokkaido University Graduate School Of Medicine
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Tamaki Nagara
Hokkaido Univ. Hokkaido Jpn
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Tamaki Nagara
Hokkaido University Nuclear Medicine
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Tamaki Nagara
Department Of Nuclear Medicine Hokkaido University School Of Medicine
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Kuroda Satoshi
Hokkaido University Graduate School Of Medicine Department Of Neurosurgery
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Nakata Tomoaki
Department Of Cardiology Sapporo Medical University School Of Medicine
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MOTEGI Hiroaki
Hokkaido University Graduate School of Medicine, Department of Neurosurgery
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NAKAYAMA Naoki
Hokkaido University Graduate School of Medicine, Department of Neurosurgery
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HIRATA Kenji
Hokkaido University Graduate School of Medicine, Department of Nuclear Medicine
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SHIGA Tohru
Hokkaido University Graduate School of Medicine, Department of Nuclear Medicine
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Shiga Tohru
Hokkaido University Graduate School Of Medicine Department Of Nuclear Medicine
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Hirata Kenji
Hokkaido University Graduate School Of Medicine Department Of Nuclear Medicine
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Motegi Hiroaki
Hokkaido University Graduate School Of Medicine Department Of Neurosurgery
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Tamaki Nagara
Hokkaido University School Of Medicine Department Of Tracer Kinetics And Department Of Nuclear Medic
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Tamaki Nagara
Hokkaido University Graduate School Of Medicine Department Of Nuclear Medicine
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Nakayama Naoki
Hokkaido University Graduate School Of Medicine Department Of Neurosurgery
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中山 若樹
Department of Neurosurgery, Hokkaido University Graduate School of Medicine
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