Heterogeneous Reduction of Myocardial Oxidative Metabolism in Patients With Ischemic and Dilated Cardiomyopathy Using C-ll Acetate PET

スポンサーリンク

概要

• 論文の詳細を見る

• Background The ^<11>C-acetate positron emission tomography can estimate myocardial oxidative metabolism, but previous studies have only evaluated small populations and the difference between ischemic (ICM) and idio-pathic dilated cardiomyopathy (DCM) has not been fully investigated. The present aims were to evaluate global and regional myocardial oxidative metabolism in a well-characterized, large population with left ventricular (LV) dysfunction in order to clarify the metabolic differences between ICM and DCM. Methods and Results Seventy-eight patients with ejection fraction (EF) ≤50% (33 ICM; 45 DCM) were compared with 14 healthy controls. Myocardial oxidative metabolism was estimated with a clearance rate constant (K_<mono>) and the coefficient of variation (CV) of regional K_<mono>. Patients with LV dysfunction had reduced K_<mono> and higher CV (p<0.05). In the comparison of oxidative alterations with clinical variables there was a weak correlation between K_<mono> and LVEF (r=0.27). Although K_<mono> was reduced in both ICM and DCM, CV was more pronouncedly increased in ICM (p=0.001). In multivariate analysis, the presence of left bundle branch block (LBBB) was an independent predictor of heterogeneous oxidative metabolism in DCM (R^2=0.30, p<0.0001). Conclusions Global reduction of myocardial oxidative metabolism occurred in both ICM and DCM. Hetero-geneous oxidative metabolism was observed in these patients, especially those with ICM. Furthermore, LBBB was the independent predictor of heterogeneous oxidative metabolism in patients with DCM.

• 社団法人日本循環器学会の論文
• 2008-04-20

著者

• Tsutsui Hiroyuki

  Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Hokkaido University

• MORITA Koichi

  Department of Virology, Institute of Tropical Medicine, Nagasaki University, and Core Research for E

• Tsukamoto Takahiro

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Tamaki Nagara

  Department of Nuclear Medicine, Graduate School of Medicine, Hokkaido University

• Yoshida K

  Furukawa City Hospital

• Yoshinaga Kaoru

  The Second Department Of Internal Medicine Tohoku University School Of Medicine

• KOMATSU Hiroshi

  Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine

• Naya Masanao

  Department of Cardiovascular Medicine, Hokkaido University

• Yoshinaga Keiichiro

  Department of Nuclear Medicine, Hokkaido University

• Morita Koichi

  台湾

• Morita Koichi

  Department Of Nuclear Medicine Hokkaido University Graduate School Of Medicine

• Morita K

  Department Of Nuclear Medicine Hokkaido University Graduate School Of Medicine

• Tamaki Nagara

  台湾

• Togashi Hiroko

  北海道大学 医学研究科 薬理

• Togashi Hiroko

  北海道大学

• Togashi Hiroko

  Department Of Pharmacology Hokkaido University School Of Medicine

• Kuge Yuji

  Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto Univer

• Wu Yen-Wen

  Department of Nuclear Medicine, National Taiwan University Hospital and National Taiwan University C

• Tsutsui Hiroyuki

  Department Of Cardiovascular Medicine

• Nakata Tomoaki

  Second Department Of Internal Medicine Sapporo Medicine University

• Togashi Hiroko

  Department Of Pharmacology Hokkaido University Graduate School Of Medicine

• Naya Masanao

  Department Of Cardiovascular Medicine Hokkaido University

• Naya Masanao

  Department Of Cardiology Hokkaido University Hospital

• Tamaki Nagara

  Hokkaido University School Of Medicine Department Of Tracer Kinetics And Department Of Nuclear Medic

• Komatsu Hiroshi

  Department Of Cardiovascular Medicine Hokkaido University Graduate School Of Medicine

• Wu Yen-wen

  Department Of Nuclear Medicine National Taiwan University Hospital And National Taiwan University Co

• Togashi Hiroko

  Safety Research Institute For Chemical Compounds

• Tsukamoto Takahiro

  Department Of Cardiovascular Medicine Hokkaido University Graduate School Of Medicine

• Yoshinaga Keiichirou

  Department Of Nuclear Medicine Hokkaido University

• Yoshinaga Keiichiro

  Department Of Cardiology Kagoshima City Medical Association Hospital

• Morita Koichi

  Department Of Forest And Forest Products Science Faculty Of Agriculture Kyushu University

• Togashi Hiroko

  Department Of Cardiovascular Medicine Hokkaido University Graduate School Of Medicine

• Morita Ken

  Section Of Urology Kushiro City General Hospital

• Kuge Yuji

  Department Of Tracer Kinetics Hokkaido University School Of Medicine

• Kuge Y

  Hokkaido Univ. Sapporo Jpn

• Kuge Yuji

  Department Of Nuclear Medicine Graduate School Of Medicine Hokkaido University

• Tamaki Nagara

  Department Of Cardiology Shiga Prefecture Medical Center For Adult

• Tamaki Nagara

  Hokkaido University Nuclear Medicine

• Yoshinaga Keiichiro

  Department Of Nuclear Medicine Hokkaido University

• Yoshinaga Keiichiro

  Department Of Photobiology Hokkaido University Graduate School Of Medicine

• Komatsu Hiroshi

  Department Of Anesthesiology Hiraka General Hospital

• Kuge Yuji

  Central Institute Of Isotope Science Hokkaido University

• Tamaki Nagara

  Department Of Nuclear Medicine Hokkaido University School Of Medicine

• Tamaki Nagara

  Hokkaido University School Of Medicine Department Of Tracer Kinetics And Department Of Nuclear Medic

• Yoshinaga Keiichiro

  Department Of Photobiology Division Of Molecular Cellular Imaging Hokkaido University Graduate Schoo

• Tamaki Nagara

  Hokkaido University Graduate School Of Medicine Department Of Nuclear Medicine

• Komatsu Hiroshi

  Departments Of Cardiovascular Medicine Hokkaido University

• TSUTSUI Hiroyuki

  Department of Cardiology, Iizuka Hospital

関連論文

• Body Mass Index can Similarly Predict the Presence of Multiple Cardiovascular Risk Factors in Middle-aged Japanese Subjects as Waist Circumference
• Discharge use of angiotensin receptor blockers provides comparable effects with angiotensin-converting enzyme inhibitors on outcomes in patients hospitalized for heart failure
• 7 Anxiety and Poor Social Support are Independently Associated with Adverse Outcomes in Patients with Mild Heart Failure(Is Stress a Risk of Cardiovascular Disease?,Symposium 22 (SY-22) (I),The 73rd Annual Scientific Meeting of The Japanese Circulation So
• 7 Anxiety and Poor Social Support are Independently Associated with Adverse Outcomes in Patients with Mild Heart Failure(Is Stress a Risk of Cardiovascular Disease?,Symposium 22 (SY-22) (I),The 73rd Annual Scientific Meeting of The Japanese Circulation So
• Which is most Beneficial for Preserving Cardiac Function and Coronary Microvasculaturein DCM, ACE-I, ARB or Two in Combination? (Cardiac Hypertrophy/Cardiomyopathy 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Eplerenone Prevents Cardiac Fibrosis through the Inhibition of OPN Expression (Cardiac Hypertrophy, Basic (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Osteopontin is Essential for Angiotensin II-Induced Cardiac Fibrosis(Heart Failure, Basic 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Angiotensin II Receptor Blocker, Valsartan, Increases Myocardial Blood Volume and Regresses Hypertrophy in Hypertensive Patients
• Effects of Atrial Fibrillation on Long-Term Outcomes in Patients Hospitalized for Heart Failure in Japan : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Anemia is an Independent Predictor of Long-Term Adverse Outcomes in Patients Hospitalized With Heart Failure in Japan : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Chronic Kidney Disease as an Independent Risk for Long-Term Adverse Outcomes in Patients Hospitalized With Heart Failure in Japan : Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• 6 Long-term Outcomes of Patients with Preserved Systolic Function Hospitalized for Heart Failure : an Analysis from JCARE-CARD(Pathophysiology and Therapeutic Strategy of Diastolic Dysfunction in Heart Failure,Plenary Session 4 (PL-4) (IHD),The 73rd Annua
• PJ-907 Oxydative Stress Impairs Mitochondrial Respiration in Skeletal Muscle and Limits Exercise Capacity in Diabetic Mice(Metabolism / Biochemistry / Energetics(03)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulatio
• OJ-095 Impairment of insulin signaling by oxidative stress in skeletal muscle causes insulin resistance in mice with heart failure.(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• OE-372 Angiotensin II-induced Oxidative Stress Impairs Mitochondrial Energy Metabolism in Lower Extremity Skeletal Muscle and Limits Exercise Capacity in Mice(Neurohumoral factors(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the
• Angiotensin II Type 1 Receptor Blocker Attenuates Myocardial Remodeling and Preserves Diastolic Function in Diabetic Heart
• PJ-120 Exercise Capacity is Limited in Diabetic Mice due to the Impairment of Aerobic Oxidative Capacity in Skeletal Muscle(Metabolism/Biochemistry/Energetics-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• 6 Long-term Outcomes of Patients with Preserved Systolic Function Hospitalized for Heart Failure : an Analysis from JCARE-CARD(Pathophysiology and Therapeutic Strategy of Diastolic Dysfunction in Heart Failure,Plenary Session 4 (PL-4) (IHD),The 73rd Annua
• PJ-907 Oxydative Stress Impairs Mitochondrial Respiration in Skeletal Muscle and Limits Exercise Capacity in Diabetic Mice(Metabolism / Biochemistry / Energetics(03)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulatio
• OJ-095 Impairment of insulin signaling by oxidative stress in skeletal muscle causes insulin resistance in mice with heart failure.(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• OE-372 Angiotensin II-induced Oxidative Stress Impairs Mitochondrial Energy Metabolism in Lower Extremity Skeletal Muscle and Limits Exercise Capacity in Mice(Neurohumoral factors(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the
• 6 Long-term Outcomes of Patients with Preserved Systolic Function Hospitalized for Heart Failure : an Analysis from JCARE-CARD(Pathophysiology and Therapeutic Strategy of Diastolic Dysfunction in Heart Failure,Plenary Session 4 (PL-4) (IHD),The 73rd Annua
• PJ-907 Oxydative Stress Impairs Mitochondrial Respiration in Skeletal Muscle and Limits Exercise Capacity in Diabetic Mice(Metabolism / Biochemistry / Energetics(03)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulatio
• OJ-095 Impairment of insulin signaling by oxidative stress in skeletal muscle causes insulin resistance in mice with heart failure.(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• OE-372 Angiotensin II-induced Oxidative Stress Impairs Mitochondrial Energy Metabolism in Lower Extremity Skeletal Muscle and Limits Exercise Capacity in Mice(Neurohumoral factors(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the
• 6 Long-term Outcomes of Patients with Preserved Systolic Function Hospitalized for Heart Failure : an Analysis from JCARE-CARD(Pathophysiology and Therapeutic Strategy of Diastolic Dysfunction in Heart Failure,Plenary Session 4 (PL-4) (IHD),The 73rd Annua
• PJ-907 Oxydative Stress Impairs Mitochondrial Respiration in Skeletal Muscle and Limits Exercise Capacity in Diabetic Mice(Metabolism / Biochemistry / Energetics(03)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulatio
• OJ-095 Impairment of insulin signaling by oxidative stress in skeletal muscle causes insulin resistance in mice with heart failure.(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• OE-372 Angiotensin II-induced Oxidative Stress Impairs Mitochondrial Energy Metabolism in Lower Extremity Skeletal Muscle and Limits Exercise Capacity in Mice(Neurohumoral factors(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the
• OE-084 Surgical Ventricular Reconstruction Improves Myocardial Oxidative Efficiency Assessed by ^ C-acetate PET and Echocardiography in Patients with Severe Heart Failure(OE15,Cardiac Function (Clinical) (M),Oral Presentation (English),The 73rd Annual
• Absence of a Trafficking Defect in R1232W/T1620M, a Double SCN5A Mutant Responsible for Brugada Syndrome
• 6 Long-term Outcomes of Patients with Preserved Systolic Function Hospitalized for Heart Failure : an Analysis from JCARE-CARD(Pathophysiology and Therapeutic Strategy of Diastolic Dysfunction in Heart Failure,Plenary Session 4 (PL-4) (IHD),The 73rd Annua
• PJ-907 Oxydative Stress Impairs Mitochondrial Respiration in Skeletal Muscle and Limits Exercise Capacity in Diabetic Mice(Metabolism / Biochemistry / Energetics(03)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulatio
• OJ-095 Impairment of insulin signaling by oxidative stress in skeletal muscle causes insulin resistance in mice with heart failure.(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soci
• OE-372 Angiotensin II-induced Oxidative Stress Impairs Mitochondrial Energy Metabolism in Lower Extremity Skeletal Muscle and Limits Exercise Capacity in Mice(Neurohumoral factors(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the
• Discharge use of angiotensin receptor blockers provides comparable effects with angiotensin-converting enzyme inhibitors on outcomes in patients hospitalized for heart failure
• OJ-152 Do JCD, IDF and NCEP Criteria of Metabolic Syndrome Predict Cardiovascular Events? : 3-Year Cohort Study of 3,343 Japanese Men(Preventive medicine / Epidemiology / Education(02)(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of
• OJ-191 Remarkable Effects of Continuous Blood Flow Restriction during Multiple Sets of Low Intensity Resistance Exercise(OJ32,Exercise Test/Cardiac Rehabilitation (H),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulat
• OJ-145 Optimizing a Protocol of Low Intensity Resistance Training with Blood Flow Restriction(Exercise test / Cardiac rehabilitation(02)(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• 4 The Role of Reactive Oxygen Species on Exercise Capacity in Chronic Heart Failure(Oxidative Stress and Cardiovascular Disease, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-309 Angiotensin II Impairs Skeletal Muscle Properties and Limits Exercise Capacity(PJ052,Hypertension, Basic (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-026 Pravastatin Ameliorates the Development of High Fat Diet-induced Diabetes by Inhibiting Oxidative Stress and Insulin Signaling Defects in Skeletal Muscle(PJ005,Diabetes 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japan
• OE-259 Lowered Aerobic Exercise Capacity was Associated with Impaired Skeletal Muscle Energy Metabolism in Patients with Metabolic Syndrome(OE44,Exercise Test/Cardiac Rehabilitation (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The
• Oxidative Stress and Mitochondrial DNA Damage in Heart Failure(Molecular Mechanisms)
• 8 Management of the "Real World" Patients with Heart Failure in Japan : JCARE and J-HOMECARE trial(Symposium 18 (SY-18) (H) How can we Make the Best Use of Japanese Evidences for Future Guidelines,Special Program,The 72nd Annual Scientific Meeting of the
• Characteristics and Outcomes of Patients With Heart Failure in General Practices and Hospitals : Japanese Cardiac Registry of Heart Failure in General Practice(JCARE-GENERAL)
• Suppressive Effects of the Single Dose of Colestimide on the Postprandial Serum Lipid Levels in Healthy Adult Male Volunteers(Lipid Disorders 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-426 NAD(P)H Oxidase-derived Oxidative Stress Causes the Exacerbation of Left Ventricular Remodeling and Failure in Diabetes-associated Myocardial Infarction(Heart failure, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Lower High-Density Lipoprotein Cholesterol is a Significant and Independent Risk for Coronary Artery Disease in Japanese Men
• Metabolic syndrome is a significant and independent risk factor for increased arterial stiffness in Japanese subjects
• PJ-195 Decreased Glomerular Filtration Rate is a Significant and Independent Risk for In-Hospital Mortality in Japanese Patients with Acute Myocardial Infarction(PJ033,Preventive Medicine/Epidemiology/Education 1 (H),Poster Session (Japanese),The 73rd Ann
• OJ-223 Risk Factors and the Incidence of Coronary Artery Disease in Japanese Men Aged Less than 50 years(Preventive medicine/Epidemiology/Education-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-056 Fasting Triglyceride is an Independent Risk Factor for Coronary Artery Disease among Japanese Middle-Aged Men : 10-Year Cohort with 6,966 Participants(Preventive medicine/Epidemiology/Education-2 (H) OJ10,Oral Presentation (Japanese),The 70th Anniv
• Fasting triglyceride is a significant risk factor for coronary artery disease in middle-aged Japanese men : Results From a 10-Year Cohort Study
• 3 The Role of Angiotensin II and Reactive Oxygen Species on Exercise Capacity in Heart Failure(Symposium 7 (SY-07) (M) Molecular Mechanism and Novel Therapeutic Target in Heart Failure,Special Program,The 72nd Annual Scientific Meeting of the Japanese Cir
• Total Occlusion of Inferior Vena Cava in a Patient With Antiphospholipid Antibody Syndrome Associated With Behcet's Disease
• PJ-098 Effects of Smoking Cessation on Coronary Endothelial Dysfunction in Young and Middle-aged Healthy Smokers(PJ017,Nuclear Cardiology (PET) (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Heterogeneous Reduction of Myocardial Oxidative Metabolism in Patients With Ischemic and Dilated Cardiomyopathy Using C-ll Acetate PET
• PJ-876 Myocardial β-adrenergic Receptor Density Assessed by ^C-CGP-PET Can Predict the Improvement of LVEF After Carvedilol in Patients with dilated cardiomyopathy(Heart failure, clinical(21)(M),Poster Session(Japanese),The 72nd Annual Scientific Meet
• Plasma Interleukin-6 and Tumor Necrosis Factor-α Can Predict Coronary Endothelial Dysfunction in Hypertensive Patients
• FRS-098 Relationship between Plasma Interleukin-6, Tumor Necrosis Factor-α, and Coronary Endothelial Dysfunction Assessed by , ^O-water PET in Hypertensive(Pathogenesis, Diagnosis and Complication of Hypertension, The 71st Annual Scientific Meeting of
• FRS-016 Decreased Myocardial Beta-adrenergic Receptor Density in Relation to Increased Sympathetic Tone in Patients with Nonischemic Cardiomyopathy : PET Study with ^C-CGP-12177(Advances in Nuclear Cardiology-1 (I) FRS4,Featured Research Session,The 7
• 3 Quantitative Assessment of Coronary Endothelial Function Using PET and Effects of Angiotensin Receptor Blockade Therapy in Patients with Hypertension(Advances in Cardiovascular Imaging,Symposium 7 (SY7) (I),The 70th Anniversary Annual Scientific Meeting
• Quantitative Assessment of Regional Myocardial Blood Flow and Myocardial Flow Reserve Using Tc-99m-sestamibi Imaging(Nuclear Cardiology 4 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Assessment of Myocardial Beta-adrenergic Receptor Density in Patients with Congestive Heart Failure : PET Study with C-11-labeled-CGP-12177(Nuclear Cardiology 6 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Papillary Muscle Suspension Concomitant With Approximation for Functional Mitral Regurgitation
• FRS-119 Familial Isolated Cardiac Conduction Defect Associated with a Mutation in the Connexin40 Gene GJA5(FRS24,Novel Mechanisms of Ventricular Arrhythmia (A),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulat
• Anxiety and Poor Social Support are Independently Associated With Adverse Outcomes in Patients With Mild Heart Failure(Heart Failure)
• Evaluation of Effects of Polymorphism for Metabolic Enzymes on Pharmacokinetics of Carvedilol by Population Pharmacokinetic Analysis(Biopharmacy)
• A fundamental study for quantitative measurement of ultrasound contrast concentration by low mechanical index contrast ultrasonography
• PJ-413 Paced QRS Prolongation is Associated with the Vulnerability to Ventricular Fibrillation by the T-wave Shock(PJ070,Ventricular Arrhythmia (Clinical/Diagnosis/Treatment) 1 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japane
• The usefulness of dipyridamole thallium-201 single photon emission computed tomography for predicting perioperative cardiac events in patients undergoing non-cardiac vascular surgery
• HDL-Cholesterol is an Important Predictor of Coronary Artery Disease among middle-Aged Men : 10-Year Follow-Up of Cohort of 6146 White-color Workers (Preventive Medicine/Epidemiology/Education/Health Policy 6 (H), The 69th Annual Scientific Meeting of the
• A BASIC STUDY ON A NEW SATELLITE ALGORITHM FOR SNOW BY CONSIDERING THE EFFECTS OF SNOW GRAIN SIZE
• Elevated Serum C-Reactive Protein Levels as a Predictive Indicator for Subsequent Renal Impairment in Patients with Acute Heart Failure
• OE-167 Tenascin-C Promotes Cardiac Remodeling and Hypertrophy during Myocardial Repair.(Molecular biology, myocardium (M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Lipoprotein Metabolism, Insulin Resistance, and Adipocytokine Levels in Japanese Female Adolescents With a Normal Body Mass Index and High Body Fat Mass(Vascular Medicine)
• Simvastatin Improves Endothelial Function Due to Its Effects on Lipids and Pleiotropic Effects in Patients With Chronic Hemodialysis(Lipid Disorders 4 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Molecular and Functional Characterization of a Novel Regulator of Carnitine Transporter OCTN2(Metabolism/Biochemistry/Energetics 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Impaired Activation of ATP-sensitive K^+ channels in Endocardial Cells from Left Ventricular Hypertrophy(Excitation-contraction Coupling/Ion Channel 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• -0789-CLINICAL CHARACTERISTICS AND PREDISPOSING FACTORS OF POSTOPERATIVE MYOCARDIAL INFARCTION IN NONCARDIAC SURGICAL PATIENTS
• -393-CARDIOTONIC EFFECTS OF TRAPIDIL : EFFECTS ON CONGESTIVE HEART FAILURE WITH ATRIAL FIBRILLATION BRADYCARDIA : Cardiovascular Drugs : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -310-DETECTION OF TRANSIENT MYOCARDIAL ISCHEMIA IN MYOCARDIAL INFARCTION : Excercise Test : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• OE-107 Long-Term Inhibition of Rho-Kinase Suppresses Left Ventricular Remodeling After Myocardial Infarction in Mice(Heart Failure, Basic 1 (M) : OE13)(Oral Presentation (English))
• Disruption of Inducible Nitric Oxide Synthase Improved Beta-Adrenergic Inotropic Responsiveness but not the Survival of Cytokine-Induced Cardiomyopathy
• Oxidative Stress in Heart Failure : The Role of Mitochondria
• PJ-094 Plasminogen Activator Inhibitor-1 Protects Coronary Vascular Wall and Prevents Cardiac Fibrosis in PAI-1-/-, ApoE-/- Mice(PJ016,Molecular Biology/Genetics, Myocardium, Vascular (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The
• Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy : analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging
• PJ-169 Abnormal Apical Rotation in Patients with Left Ventricular Hypertrophy Determined by Two-Dimensional Ultrasound Speckle Tracking Imaging(Echo/Doppler-13 (I) PJ29,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japane
• PE-584 Plasma NT-proBNP Concentration is a Sensitive Marker of Diastolic Dysfunction and Arterial Remodeling in Hypertension(Hypertension, clinical-7 (H) PE102,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circula
• Usefulness of Left Parasternal Approach for the Continuous-Wave Doppler Measurement of Left Ventricular Outflow Tract Pressure Gradient in Patients With Hypertrophic Cardiomyopathy
• Depressive Symptoms are the Strongest Predictor of Quality of Life in Patients with Atrial Fibrillation(Arrhythmia, Diagnosis/Pathophysiology/EPS 11 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Induction of c-fos mRNA Expression by Pure Pressure Overload in Cultured Cardiac Myocytes
• Angiotensin converting enzyme inhibitors attenuated the expression of G-protein coupled receptor kinases in heart failure patients
• Chronic beta-adrenergic receptor stimulation enhances the expression of G-Protein coupled receptor kinases, GRK2 and GRK5, in both the heart and peripheral lymphocytes
• Myocardial Blood Volume Assessed by Contrast Echocardiography is Associated with Contractile Reserve in Patients with Idiopathic Dilated Cardiomyopathy(Echo/Doppler 7 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-552 Diagnostic Accuracy of New Generator-produced 82Rubidium Myocardial Perfusion Positron Emission Tomography in the Detection of Coronary Artery Disease(Nuclear cardiology(06)(I),Poster Session(English),The 72nd Annual Scientific Meeting of the Japan
• OE-148 Atorvastatin Increases Cholesterol Absorption and Serum CXCL16 Levels in Patients with Acute Coroary Syndrome Compared with Pravastatin(OE25,ACS/AMI (Clinical/Treatment) 1 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The
• PE-426 Overexpression of mitochondrial transcription factor A protects failing myocardium from oxidative stress(Heart failure, basic(04)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

もっと見る 閉じる

スポンサーリンク