Anxiety and Poor Social Support are Independently Associated With Adverse Outcomes in Patients With Mild Heart Failure(Heart Failure)

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Background The impact of psychosocial states, such as depression or anxiety, and social support on the out-comes of stable outpatients with mild heart failure (HF) has not been evaluated in the "real world" clinical practice. Methods and Results In the present study, 139 patients with a prior history of admission for HF provided the baseline demographic, clinical, socio-environmental, and psychosocial information. Cardiac death or re-admission because of worsening of HF was monitored during the follow-up period of 1 year. The prevalence of depression and anxiety were 37% and 37%, respectively, in HF patients. Depression was independently associated with male (sβ=-0.36, P=0.01), social ties (sβ=0.22, P=0.04) and low social support (sβ=-0.39, P<0.01). Anxiety was associated with alcohol drinking(sβ=0.22, P=0.04), brain natriuretic peptide≥200 Pg/dl (sβ=0.35, P<0.01), and low social support(sβ=-0.28, P=0.01). Kaplan-Meier analysis demonstrated that patients with anxiety (log-lanktest; P<0.01) and lower scores of social support (P<0.01) had a higher rate of HF-related re-admission. Conclusions Anxiety and low social support were independently associated with HF-related re-admission, which indicates the need for their inclusion in the assessment and management of HF.
社団法人日本循環器学会の論文
2009-01-20