Novel Compounds of Octahydroheptaprenyl Mycolic Acyl Ester and Monocyclic C_<35>-Terpene, Heptaprenylcycline B, from Non-Pathogenic Mycobacterium Species
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概要
- 論文の詳細を見る
A search for C35-terpenes from non-saponified extracts of 12 non-pathogenic Mycobacterium species was carried out. Octahydroheptaprenyl mycolic acyl esters were isolated from M. chlorophenolicum cells which were also found from M. thermoresistibile, M. vanbaalenii, M. aichiense, M. smegmatis, and M. parafortuitum. This is the first report on a polyprenol esterified by a mycolate. A novel monocyclic C35-terpene possessing a ketone, named heptaprenylcycline B, was isolated, which was detected from M. chlorophenolicum and M. vanbaalenii. The biosynthetic pathway to heptaprenylcycline B was investigated with ancymidol which acts as an inhibitor of a P450 monooxygenase. This experiment suggested that the P450 monooxygenase may be responsible for the production of heptaprenylcycline B.
- 社団法人 日本農芸化学会の論文
- 2010-01-23
著者
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Ono Eri
Department Of Applied Biological Chemistry Faculty Of Agriculture And Graduate School Of Science And
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Sato Tsutomu
Department Of Applied Biological Chemistry Faculty Of Agriculture And Graduate School Of Science And
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Hoshino Tsutomu
Department Of Applied Biological Chemistry Faculty Of Agriculture And Graduate School Of Science And
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Hoshino Tsutomu
Department Of Agricultural Chemistry Faculty Of Agriculture Niigata University
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Takagi Ryosuke
Department Of Applied Biological Chemistry Faculty Of Agriculture And Graduate School Of Science And
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ORITO Yuriko
Department of Applied Biological Chemistry, Faculty of Agriculture, and Graduate School of Science a
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Orito Yuriko
Department Of Applied Biological Chemistry Faculty Of Agriculture And Graduate School Of Science And
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Sato Tsutomu
Department Of Agricultural Chemistry Faculty Of Agriculture Yamaguchi University
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Sato Tsutomu
Departmenet of Physics,Faculty of Sience,Hirosaki University
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