Amount and Frequency of Alcohol Consumption and All-Cause Mortality in a Japanese Population : The JMS Cohort Study
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概要
- 論文の詳細を見る
Background: Lower mortality has been reported in light-to-moderate alcohol drinkers. We examined the association between the amount and frequency of alcohol consumption and all-cause mortality in a Japanese population.Methods: We conducted a prospective cohort study among 8934 Japanese people (3444 men and 5490 women) who completed a baseline survey between 1992 and 1995. We confirmed the date and cause of death by referring to death certificates. The Cox proportional hazards model was used to evaluate the effect of alcohol consumption on risk for all-cause mortality, after adjustment for potential confounding factors.Results: We identified 637 (397 men and 240 women) deaths during the 12.0 years of mean follow-up. Among men, as compared with non-drinkers, the relative risk was higher in ex-drinkers (hazard ratio [HR], 1.18), lower in light drinkers (HR, 0.95) and moderate drinkers (HR, 0.91), and significantly higher in heavy drinkers (HR, 1.67; 95% confidence interval, 1.10–2.55). Among women, light, moderate, and heavy drinkers were grouped into current drinkers. The relative risk was slightly higher in current drinkers (HR, 1.23), and that in ex-drinkers was near 1.0 (HR, 0.97). In stratified analysis, the harmful effects of heavy drinking were more severe among male smokers and younger men. In terms of frequency, men who drank only on special occasions had the highest mortality (HR, 1.28), regardless of alcohol intake per drinking session.Conclusions: In men, a near J-shaped association was identified between alcohol consumption and all-cause mortality. Both the amount and frequency of alcohol consumption were related to mortality.
- 日本疫学会の論文
- 2009-05-01
著者
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Nakamura Yosikazu
Department of Public Health, Jichi Medical University
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Sadakane Atsuko
Department of Public Health, Jichi Medical University
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ISHIKAWA Shizukiyo
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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GOTOH Tadao
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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Kayaba Kazunori
Department Of Cardiology Jichi Medical University
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Kario Kazuomi
自治医科大学 地域医療学
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Nakamura Y
Department Of Public Health Jichi Medical University
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Gotoh Tadao
Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University
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Gotoh Tadao
自治医科大学地域医療学センター 地域医療学
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Gotoh Tadao
自治医科大学地域医療学センター 地域医療学部門
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Gotoh Tadao
自治医科大学 公衆衛生学
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Nakamura Yosikazu
自治医科大学地域医療学センター 地域医療学
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Nakamura Yosikazu
千代田区千代田保健所
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Kayaba Kazunori
Saitama Prefectural University, School of Health and Social Sciences.
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Kayaba Kazunori
自治医科大学 地域医療学
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Kayaba Kazunori
Saitama Prefectural University
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Gotoh Tadao
自治医科大学 地域医療学
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Gotoh Tadao
Wara National Insurance Hospital
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Ishikawa Shizukiyo
Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University
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Ishikawa Shizukiyo
自治医科大学 医学部循環器内科学
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Ishikawa Shizukiyo
自治医科大学地域医療学センター
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Ishikawa Shizukiyo
自治医科大学地域医療学センター 地域医療学部門
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Ishikawa Suzukiyo
南郷村国民健康保険病院
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Kitamura K
Faculty Of Medicine Department Of Internal Medicine Division Of Circulatory And Body Fluid Regulatio
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Kohara Katsuhiko
Department Of Geriatric Medicine Ehime Unviersity School Of Medicine
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Kammatsuse Katsuo
Nihon University
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Nakamura Yosikazu
Department Of Health Science Division Of Epidemiology And Community Health Jichi Medical School
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Nakamura Yosikazu
Division Of Epidemiology Miyagi Cancer Center Research Institute
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Goto Tadao
Kokuho Wara Hospital
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Kitamura Kouichi
Internal Medicine Nephrology And Hypertension St. Marianna University School Of Medicine
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Ishikawa Shizukiyo
Division Of Community And Family Medicine Jichi Medical University School Of Medicine
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Kadota K
Department Of Internal Medicine Hyogo Hospital
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Komamura Kazuo
Department Of Cardiovascular Medicine National Cardiovascular Center
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Niwa Yoshimitsu
自治医科大学 公衆衛生学
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Kuwahara Koichiro
Department Of Medicine And Clinical Sciences Graduate School Of Medicine Kyoto University
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Sadakane Atsuko
Department Of Public Health Jichi Medical University
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Sadakane Atsuko
Dep. Of Public Health Jichi Medical Univ.
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Kamide Kei
Cardiovascular Division Osaka Police Hospital
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Kubota Kaoru
Division Of Internal Medicine And Thoracic Oncology National Cancer Center Hospital
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Isikawa Sizukiyo
Department Of Cardiology Jichi Medical School
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Gotoh Tadao
Wara Health Insurance Hospital
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