Metabolic Syndrome and C-Reactive Protein in the General Population : JMS Cohort Study
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概要
- 論文の詳細を見る
Background In recent years some studies have shown that metabolic syndrome (MS) is associated with inflammation, indicated by high-sensitivity C-reactive protein (hsCRP), but there have been few population-based studies, especially in Japan. Methods and Results The study subjects were 2,191 men and women examined between 1992 and 1995 with the necessary data to ascertain MS as part of the Jichi Medical School Cohort Study. CRP was measured by nephelometry. There were 109 subjects defined as having MS (5.0%), and the proportion of MS cases was higher in men (9.4%) than in women (1.8%). Geometric mean and median CRP in the MS group was higher than that in the non-MS (geometric mean; p<0.001, median: 0.312mg/L in MS and 0.122mg/L). Proportion of MS increased with CRP, after the subjects were divided by tertile of CRP (odds ratio, 95% confidence interval 1^<st> fertile as a reference; 2^<nd> tertile: 2.9, 1.5-5.9, 3^<rd> tertile: 5.7, 3.1-11.1). Conclusion Inflammation, measured by the concentration of hsCRP, was elevated in cases of MS in the general Japanese population. Longitudinal data should be examined in the future.
- 社団法人日本循環器学会の論文
- 2006-12-20
著者
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ISHIKAWA Shizukiyo
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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KAYABA Kazunori
School of Health and Social Services, Saitama Prefectural University
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GOTOH Tadao
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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KAJII Eiji
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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Nakamura Y
Department Of Public Health Jichi Medical University
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Gotoh Tadao
Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University
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Gotoh Tadao
自治医科大学地域医療学センター 地域医療学
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Gotoh Tadao
自治医科大学地域医療学センター 地域医療学部門
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Gotoh Tadao
自治医科大学 公衆衛生学
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Nakamura Yosikazu
自治医科大学地域医療学センター 地域医療学
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Nakamura Yosikazu
千代田区千代田保健所
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Kayaba Kazunori
自治医科大学 地域医療学
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Gotoh Tadao
自治医科大学 地域医療学
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Ishikawa Shizukiyo
Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University
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Ishikawa Shizukiyo
自治医科大学 医学部循環器内科学
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Ishikawa Shizukiyo
自治医科大学地域医療学センター
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Ishikawa Shizukiyo
自治医科大学地域医療学センター 地域医療学部門
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NAKAMURA Yosikazu
Division of Public Health, Jichi Medical University School of Medicine
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Kajii Eiji
Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University
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Kajii Eiji
自治医科大学 地域医療学
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Kayaba Kazunori
School Of Health And Social Services Saitama Prefectural Univ.
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Nakamura Yosikazu
Division Of Epidemiology Miyagi Cancer Center Research Institute
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Goto Tadao
Kokuho Wara Hospital
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Ishikawa Shizukiyo
Division Of Community And Family Medicine Jichi Medical University School Of Medicine
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Niwa Yoshimitsu
自治医科大学 公衆衛生学
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Nakamura Yosikazu
Division Of Cardiology Department Of Medicine Shiga University Of Medical Science
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Kajii Eiji
Division Of Community And Family Medicine Jichi Medical University
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Isikawa Sizukiyo
Department Of Cardiology Jichi Medical School
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