Metabolic Syndrome Mortality in a Population-Based Cohort Study : Jichi Medical School (JMS) Cohort Study

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概要

• 論文の詳細を見る

• BACKGROUND: Metabolic syndrome is known to increase morbidity and mortality of cardiovascular disease. The National Cholesterol Education Program Adult Treatment Expert Panel III in 2001 (revised in 2005) and the Japanese definition of metabolic syndrome were launched in 2005. No study regarding the association between metabolic syndrome by Japanese definition and mortality has been performed. The aim of this study was to clarify the prevalence of metabolic syndrome and its effects to mortality in a population-based cohort study.METHODS: A total of 2176 subjects who satisfied the necessary criteria for metabolic syndrome were examined between 1992 and 1995 as a part of Jichi Medical School Cohort Study by Japanese definition. Coxs proportional hazard models were used to analyze the association of metabolic syndrome with mortality.RESULTS: The prevalence of metabolic syndrome was 9.0% in males and 1.7% in females. There were 17 deaths (14 males), including 6 cardiovascular deaths (5 males), during a 12.5-year follow-up period among metabolic syndrome subjects. After adjusting for age, smoking status, and alcohol drinking status, the hazard ratio (95% confidence interval) for all-cause mortality was 1.13 (0.64-1.98) in males and 1.31 (0.41-4.18) in females, and HR for cardiovascular mortality was 1.84 (0.68-4.96) in males, and 1.31 (0.17-9.96) in females.CONCLUSION: No statistical significant relationship between metabolic syndrome by Japanese definition and all-cause mortality was observed in a population-based cohort study.J Epidemiol 2007; 17: 203-209.

• 日本疫学会の論文
• 2007-11-01

著者

• Nakamura Yosikazu

  Department of Public Health, Jichi Medical University

• ISHIKAWA Shizukiyo

  Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University

• KAYABA Kazunori

  School of Health and Social Services, Saitama Prefectural University

• GOTOH Tadao

  Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University

• KAJII Eiji

  Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University

• Nakamura Y

  Department Of Public Health Jichi Medical University

• NIWA Yasunori

  Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University

• Gotoh Tadao

  Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University

• Gotoh Tadao

  自治医科大学地域医療学センター 地域医療学

• Gotoh Tadao

  自治医科大学地域医療学センター 地域医療学部門

• Gotoh Tadao

  自治医科大学 公衆衛生学

• Nakamura Yosikazu

  自治医科大学地域医療学センター 地域医療学

• Nakamura Yosikazu

  千代田区千代田保健所

• Kayaba Kazunori

  自治医科大学 地域医療学

• Gotoh Tadao

  自治医科大学 地域医療学

• Ishikawa Shizukiyo

  Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University

• Ishikawa Shizukiyo

  自治医科大学 医学部循環器内科学

• Ishikawa Shizukiyo

  自治医科大学地域医療学センター

• Ishikawa Shizukiyo

  自治医科大学地域医療学センター 地域医療学部門

• Kajii Eiji

  Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University

• Kajii Eiji

  自治医科大学 地域医療学

• Niwa Yasunori

  Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University

• Nakamura Yosikazu

  Department Of Health Science Division Of Epidemiology And Community Health Jichi Medical School

• Kayaba Kazunori

  School Of Health And Social Services Saitama Prefectural Univ.

• Nakamura Yosikazu

  Division Of Epidemiology Miyagi Cancer Center Research Institute

• Goto Tadao

  Kokuho Wara Hospital

• Ishikawa Shizukiyo

  Division Of Community And Family Medicine Jichi Medical University School Of Medicine

• Niwa Yoshimitsu

  自治医科大学 公衆衛生学

• Kajii Eiji

  Division Of Community And Family Medicine Jichi Medical University

• Isikawa Sizukiyo

  Department Of Cardiology Jichi Medical School

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