High-Density Lipoprotein and Prostate Cancer: An Overview
スポンサーリンク
概要
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Prostate cancer is a common disease in modern, developed societies and has a high incidence and mortality. High-density lipoprotein cholesterol (HDL-C) has recently received much attention as a possible risk marker of prostate cancer development and prognosis. In the present article, we summarized findings from epidemiologic studies of the association between HDL-C and prostate cancer. Low HDL-C level was found to be a risk and prognostic factor of prostate cancer in several epidemiologic studies, although the overall linkage between HDL and prostate cancer has not been definitively established. The mechanisms for this association remain uncertain; however, limited data from experimental studies imply a possible role of HDL in the pathophysiology of prostate cancer. More epidemiologic research, in combination with experimental studies, is needed in this field.
著者
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ISHIKAWA Shizukiyo
Division of Community and Family Medicine, Center for Community Medicine, Jichi Medical University
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Ishikawa Shizukiyo
Division Of Community And Family Medicine Center For Community Medicine Jichi Medical University
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Suzuki Kazuhiro
Department Of Cardiovascular Surgery Yamaguchi Grand Medical Center
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Kotani Kazuhiko
Cardiopulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health
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Sekine Yoshitaka
Cardiopulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health
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Remaley Alan
Cardiopulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health
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Ikpot Imoh
Cardiopulmonary Branch, National Heart Lung and Blood Institute, National Institutes of Health
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