Glycated Hemoglobin Levels and Their Correlation With Atherosclerotic Risk Factors in a Japanese Population : The Jichi Medical School Cohort Study 1993-1995
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概要
- 論文の詳細を見る
We conducted a large population-based study to assess levels of glycated hemoglobin A1c(HbA1c) and to evaluate the correlation between HbA1c and other cardiovascular risk factors in Japan. A total of 910 men and 1, 890 women aged 30-69 years participated in the Jichi Medical School Cohort Study (1993-95). Mean HbA1c was 5.61% in men and 5.49% in women. HbA1c levels were significantly correlated with levels of triglycerides, fibrinogen, and factor VII, and inversely correlated with high-density lipoprotein (HDL)-cholesterol level in both sexes. Lipoprotein(a) was inversely correlated in men. Blood pressure, body mass index (BMI), and total cholesterol were significantly associated with HbA1c in women. After adjusting for significant variables in univariate analyses, fibrinogen and factor VII remained as significant correlates in men, and BMI and total cholesterol in women. The authors conclude that HbA1c level is correlated not only with classical cardiovascular risk factors, but also with fibrinogen and factor VII. Our results suggest that HbA1c could be an alternative to blood glucose in evaluating atherosclerotic risk in a large-sized population study.
- 社団法人日本循環器学会の論文
- 1998-03-20
著者
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Nakamura Yosikazu
Department of Public Health, Jichi Medical University
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Kayaba Kazunori
Department Of Cardiology Jichi Medical University
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KARIO Kazuomi
Department of Cardiology, Jichi Medical University
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Nakamura Yosikazu
自治医科大学地域医療学センター 地域医療学
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Nakamura Yosikazu
千代田区千代田保健所
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Kayaba Kazunori
Department Of Cardiology And Internal Medicine Jichi Medical School
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Kario Kazuomi
米国
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MIZOOKA Masafumi
Hiroshima Prefectural Setoda Hospital
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IGARASHI Masahiro
Department of Community and Family Medicine, Jichi Medical School
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Nakamura Yosikazu
Department Of Health Science Division Of Epidemiology And Community Health Jichi Medical School
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Igarashi Masahiro
Department Of Community And Family Medicine Jichi Medical School
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Kario Kazuomi
Department Of Cardiology Jichi Medical School
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Nago Naoki
Department of Community and Family Medicine, Jichi Medical School
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Miyamoto Takeshi
Okawa National Health Insurance Clinic
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Mizooka Masafumi
Sakugi National Health Insurance Clinic
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Terada Mitsukazu
Sakugi National Health Insurance Clinic
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Nakamura Yosikazu
Division Of Epidemiology Miyagi Cancer Center Research Institute
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Nago Naoki
Community Medicine Education Center Japan Association For Development Of Community Medicine
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Kario Kazuomi
Department Of Public Health Jichi Medical University
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Niwa Yoshimitsu
自治医科大学 公衆衛生学
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Mizooka Masafumi
Division Of Community And Family Medicine Centre For Community Medicine Jichi Medical University
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Kotani Kazuhiko
Department Of Public Health Jichi Medical University
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