Impact of the Universal Hepatitis B Immunization Program in Mongolia : Achievements and Challenges
スポンサーリンク
概要
- 論文の詳細を見る
BACKGROUND: The impact of the universal infant hepatitis B (HB) immunization program initiated in 1991 in Mongolia is still unclear.METHODS: A nationwide school-based cross-sectional serosurvey was conducted in 2004, with stratified, multistage, random cluster sampling from all public elementary schools (n=593) in Mongolia. All children were tested for serological markers of hepatitis B virus (HBV).RESULTS: Serology results were available for 1,145 children (592 boys and 553 girls) aged 7-12 years (survey response rate: 93%). Immunization card was available for 702 (61.3%) children. The coverage of complete HB vaccination was 60.1% and it was increased by birth cohort from 44% to 76%. Significantly higher proportion of children in Metropolitan cities (75.2%) was completely vaccinated with HB compared to those in Province centers (55.7%) and rural areas (59.1%). HBV infection occurred in 5.9%, 13.2%, and 20.8% of complete vaccinees living in Metropolitan, Province centers, and rural areas, respectively; of whom 1.2%, 2.9%, and 8.6% were HB surface antigen (HBsAg) carriers, respectively. Only 17.0% of the children had protective anti-HBs which decreased from 31.1% to 16.3% among 7 to 12-year-olds indicating its decay with time.CONCLUSIONS: Prevalence of HBV infection and carriage among young generation meaningfully declined compared with those of previous studies in Mongolia. The coverage of birth dose and complete HB vaccination was significantly low in Province centers and rural areas which should be taken into consideration.J Epidemiol 2007; 17: 69-75.
- 日本疫学会の論文
- 2007-05-01
著者
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Nakamura Yosikazu
Department of Public Health, Jichi Medical University
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Uehara Ritei
Department of Public Health, Jichi Medical University
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WATANABE Makoto
Department of Preventive Cardiology, National Cardiovascular Center
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上原 里程
Department Of Public Health Jichi Medical University
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Nakamura Y
Human Genome Center Institute Of Medical Science University Of Tokyo
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OKI Izumi
Department of Public Health, Jichi Medical University
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OJIMA Toshiyuki
Department of Community Health and Preventive Medicine, Hamamatsu University School of Medicine
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Ojima T
Department Of Public Health Jichi Medical University School Of Medicine
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Uehara Ritei
Department Of Pediatrics Jikei University School Of Medicine
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DAVAALKHAM DAMBADARJAA
Department of Public Health, Jichi Medical University School of Medicine
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NYMADAWA PAGVAJAV
National Center for Communicable Diseases
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WIERSMA STEVEN
Department of Immunization, Vaccines and Biologicals, World Health Organization
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Watanabe Makoto
Department Of Cardiology Hirai Hospital
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Ojima Toshiyuki
Hamamatsu Univ. School Of Medicine
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Watanabe Makoto
Department Of Public Health Jichi Medical University
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Oki Izumi
Department Of Public Health Jichi Medical University
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Oki Izumi
Department Of Public Health Jichi Medical School
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Nishino Y
Jichi Medical School
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Nakamura Yosikazu
Department Of Health Science Division Of Epidemiology And Community Health Jichi Medical School
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Ojima Toshiyuki
Department Of Hygiene And Preventive Medicine Iwate Medical University
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Nakamura Yasuyuki
Department Of Health Science Shiga University Of Medical Science
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Wiersma Steven
Department Of Immunization Vaccines And Biologicals World Health Organization
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Nakamura Y
Division Of Epidemiology Miyagi Cancer Center Research Institute
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尾島 俊之
Department Of Community Health And Preventive Medicine Hamamatsu University School Of Medicine
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Ojima T
Hamamatsu Univ. School Of Medicine
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Ojima Toshiyuki
Department Of Community Health And Preventive Medicine Hamamatsu University School Of Medicine
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Niwa Yoshimitsu
自治医科大学 公衆衛生学
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Nishioka Yoshihiro
Department Of Obstetrics And Gynecology Cancer Research Institute Sapporo Medical University School
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Watanabe Makoto
Department Of Cardiology Anjo Kosei Hospital
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Watanabe Makoto
Department Of Analytical Chemistry Of Medicines. Showa Pharmaceutical University
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Nakamura Yasuyuki
滋賀医科大学 循環器内科
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Nagatani Yukihiro
Heart Rhythm Center Department Of Cardiovascular Medicine Shiga University Of Medical Science
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Davaalkham Dambadarjaa
Department Of Epidemiology And Biostatistics School Of Public Health Health Sciences University Of M
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中村 好一
Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science University Of Toky
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Watanabe Makoto
Department of Analytical Chemistry of Medicines, Showa Pharmaceutical University
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