New Topics in Vasopressin Receptors and Approach to Novel Drugs : Involvement of Vasopressin V1a and V1b Receptors in Nociceptive Responses and Morphine-Induced Effects
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概要
- 論文の詳細を見る
Arginine vasopressin (AVP) receptors have been classified into V1a, V1b, and V2 subtypes. Recent studies have demonstrated the involvement of AVP in anti-nociception and in morphine-induced anti-nociception. However, the roles of individual AVP-receptor subtypes have not been fully elucidated. Here, we have summarized the role of V1-receptor subtypes in behavioral responses to noxious stimuli and to morphine. In this review, we focus on studies using mice lacking the V1a receptor (V1a−/− mice) and the V1b receptor (V1b−/− mice).
- 社団法人 日本薬理学会の論文
- 2009-01-20
著者
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Honda Kenji
Department of Physiology and Pharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University
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Takano Yukio
Department of Physiology and Pharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University
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Takano Yukio
Department Of Physiology And Pharmacology Faculty Of Pharmaceutical Sciences Fukuoka University
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Honda Kenji
Department Of Physiology And Pharmacology Faculty Of Pharmaceutical Sciences Fukuoka University
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Takano Yukio
Department Of Applied Physics Faculty Of Engineering University Of Tokyo
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Honda Kenji
Department Of Chemistry Toho University
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