21世紀のメディシナルケミスト
スポンサーリンク
概要
- 論文の詳細を見る
- 2003-02-01
著者
-
青木 一真
三共(株)化学研究所
-
首藤 紘一
(財)乙卯研究所
-
首藤 紘一
(財)日本医療情報センター
-
西 孝夫
大塚製薬(株)
-
西 孝夫
大塚製薬(株)徳島第二工場合成研究室
-
長尾 善光
徳島大学薬学部薬化学研究室
-
仲 建彦
(株)武田分析研究所
-
長尾 善光
Graduate School Of Pharmaceutical Sciences The University Of Tokushima
-
長尾 善光
徳島大学薬学部
-
Nagao Y
Faculty Of Pharmaceutical Sciences The University Of Tokushima
-
Nagao Yoshimitsu
Faculity Of Pharmaceutical Sciences The University Of Tokushima
-
仲 建彦
武田分析研究所
関連論文
- レチノイドによる自己免疫疾患の治療
- 6.合成レチノイドAm80の医薬品化と今後の創薬展開(脂溶性ビタミン総合研究委員会第308回会議研究発表要旨)
- 2-A-16 レチノイド活性を有するトロポロン誘導体(第57回大会一般研究発表)(第57回大会研究発表要旨)
- 405 合成レチノイドTZ325の自己免疫疾患に及ぼす影響について
- 325 合成レチノイド誘導体Tp-80の実験的自己免疫疾患に及ぼす影響について
- A204 脱皮ホルモン活性物質に応答するレポータージーンアッセイの開発と新規殺虫剤クロマフェノジドの評価
- サイトカイニン特異的結合蛋白の分子同定
- パキマ酸によるPPARγの特異的活性化と脂肪細胞の分化誘導作用
- 2-I-2 α-Tocopherol誘導体(8-HM)のラットにおけるビタミンE活性 : 第49回大会一般研究発表要旨
- レチノイド アンタゴニスト
- SYNERGISTS FOR RETINOID IN CELLULAR DIFFERENTIATION OF HUMAN PROMYELOCYTIC LEUKEMIA CELLS HL-60
- P-52 ココナッツミルク中の主サイトカイニンの分離と構造決定(ポスター発表の部)
- レチノイドの作用の分離とレチノイドアンタゴニスト レセプター選択的化合物の試薬・医薬への開発
- 植物ホルモン「サイトカイニン」の構造展開と分子標的
- 植物耐病因子ベンツオキサジノンの化学
- SPECIFIC OXIDATION OF RETINOIC ACID TO 4-OXO-RETINOIC ACID IN DILUTED ACID SOLUTIONS
- 4.活性ビタミンE仮説 : ビタミンE誘導体の合成と活性 : 脂溶性ビタミン総合研究委員会 第262回会議研究発表要旨
- Retinoidal Dienamides and Related Aromatic Amides. Replacement of the 9-Ene Structure of Retinoic Acid with a trans- or cis-Amide Group
- Synthesis and Biological Activity of Carboxyphenylquinolines and Related Compounds as New Potent Retinoids. Retinobenzoic Acids. VII
- Enhancement of Human Papillomavirus Type 18 Gene Expression in HeLa Cells by 12-O-Tetradecanoylphorbol-13-acetate, 3β, 5α-Dihydroxycholestan-6-one, and Cholesterol
- RADIOSENSITIZING HYPOXIC CELLS WITH NEW 3-NITRO-1,2,4-TRIAZOLE DERIVATIVES IN VITRO AND IN VIVO
- P-21 炭酸ガスからアミノ酸誘導体への変換(ポスター発表の部)
- Intramolecular Nonbonded S…N Interaction in Rabeprazole
- Synthesis of New Quinolone Antibiotics Utilizing Azetidine Derivatives Obtained from 1-Azabicyclo[1.1.0]butane
- Effects of Magnesium Salts and Amines on the Stereoselectivity in the Imine Aldol Reaction
- Mechanistic Considerations for the Consecutive Cyclization of 2,3-Dibromopropylamine Hydrobromide Giving a Strained Molecule, 1-Azabicyclo[1.1.0]butane
- Synthesis of New Chiral Sulfinyldiacetic Acid Derivatives and Attempt at Chemoselective Asymmetric Pummerer Reaction
- 228 実験的アレルギー性脳脊髄炎(EAE)におよぼすレチノイド化合物Am-80の影響
- Radiosensitizing Hypoxic Cells with New 3-Nitro-1,2,4-triazole Derivatives In Vitro and In Vivo.
- SYNTHETIC DEVELOPMENT OF HYPOXIC CELL SENSITIZERS HAVING 3-NITROTRIAZOLE MOIETY
- 赤外線蛍光内視鏡の原理と臨床応用
- New Norepinephrine Potentiators : Synthesis and Structure-Activity Relationships of a Series of 4-Phenyl-1,2,3,4-tetrahydroisoquinolin-4-ols
- Diastereoselective Alkylation of Chiral Tin(II) Enolates onto Cyclic Acyl Iminium Ions. : Asymmetric Total Syuthesis of (-)-Supinidine.
- Highly Diastereoselective Alkylation of Chiral Tin(II) Enolates onto Cyclic Acyl Imines, An Efficient Asymmetric Synthesis of Bicyclic Alkaloids Bearing a Nitrogen Atom Ring Juncture.
- New General Asymmetric Synthesis of Versatile γ-Alkylated Butenolides and Its Application to Expeditious Synthesis of the Chiral Geissman-Waiss Lactones Useful for (+)-Retronecine Synthesis.
- PB17 SYNTHETIC STUDIES ON BICYCLIC ALKALOIDS BASED ON A NEW CHIRAL DESIGN UTILIZING VERSATILE MALALDEHYDIC ACID
- 21世紀のメディシナルケミスト
- プロセス化学は21世紀の化学
- 創薬に活躍する有機金属
- 173 マウスアレルギー性皮膚炎におよぼすレチノイド化合物Am-80の影響
- Expeditious Syntheses of Conjugated Allenyl Esters and Oxazoles through a Cascade Reaction of α-Alkynyl Malonates under Alkaline Conditions
- Enzymatic Hydrolyses of the σ-Symmetric Dicarboxylic Diesters Bearning a Sulfinyl Group as the Prochiral Center
- 抗血小板剤シロスタゾール(プレタール^)の研究開発
- P-33 α置換セリン誘導体の不斉合成を基盤とする(+)-ラクタシスチンの不斉全合成研究(ポスター発表の部)
- A New Convenient Synthesis of α-Pyrone and α-Pyridone Derivatives
- Expeditious Asymmetric Synthesis of Optically Pure δ-Lactones Bearing Consecutive Three Asymmetric Centers
- Axial Preference of Bulky Group- and Electron-Withdrawing Group-Substituted Oxygen Atom on the Chair-Type Cyclohexanone, Glutaric Anhydride, and Glutarimide.
- Synthesis, Structure, and Self-Oxidation of Alkynyl(phenyl)iodonium Periodates.
- A Facile Synthesis of Novel Chiral Phosphonoacetates Bearing a Stereogenic Phosphorus Atom
- A Facile Method for the Stereoselective Horner-Wadsworth-Emmons Reaction of Aryl Alkyl Ketones
- Synthesis and Antibacterial Activity of New 1β-Methylcarbapenems Having the Potential for Intramolecular Nonbonded S・・・O Interactions
- New Six- to Eight-Membered-Ring Formation Based on the Intramolecular Endo- Mode Ring Closure of Allenyl (Substituted Phenyl)alkyl Ketones
- Characterization of the Sulfonic Esters Adopting a Folded Conformation with Stacked Aromatic Moieties
- Stereoselective Synthesis of Tetrasubstituted (Z)-Alkenes from Aryl Alkyl Ketones Utilizing the Horner-Wadsworth-Emmons Reaction
- アフラトキシンB_1とDNAとの結合
- 1. レチノイドの医薬化学
- 岡本敏彦先生を偲んで
- フェノキセニウムイオンの生成と反応
- Efficient Synthesis of Isothiocyanates Based on the Tandem Staudinger/aza-Wittig Reactions and Mechanistic Consideration of the Tandem Reactions
- A Practical and Facile Synthesis of Azetidine Derivatives for Oral Carbapenem, L-084
- Syntheses and Pharmacokinetic Studies of Prodrug Esters for the Development of Oral Carbapenem, L-084
- On the Mechanism of Stereoisomerization of Methyl Groups of 1,3-Diaxial[cis-3-Benzyloxy)cyclohexyl]chlorodimethylstannane.
- ダイナミックヘテロ環化学を背景に創薬研究へ飽くなき挑戦
- 学術振興賞受賞 国嶋崇隆氏の業績
- 分子構造特性を基盤とする新反応の開発並びに薬学的応用研究
- 新しい酒は新しい皮袋に
- Cyclization, Ring-Expansion, and Several Cascade Reactions Utilizing Allenylic Molecular Structure Characteristics
- 現状のままで満足ですか年輩者 : 今や集学的に"熟学"事始めの時
- 薬学教育における現行の問題点と21世紀への展望(21世紀の人づくり)(21世紀:薬学の時代へ)
- α-置換セリン誘導体の不斉合成
- 技術賞受賞抗血小板剤シロスタゾールの研究開発
- 医薬への道
- H_2C^+-CH_4^+
- ヘテロ環の化学 第5集(化学の領域増刊124号) : 亀谷哲治, 加藤鐵三, 山中 宏編, B5判/350頁/4900円(南江堂)
- 新植物組織培養, 竹中正幸, 中島哲夫, 古谷力 編, B5判, 411頁, 6500円, (朝倉書店)
- 変異原化合物の核酸へのインターカレーション
- Generalization, Alteration, and Enhancement of the Stereoselectivity in the Cieplak-Mode Reductions of 4-Alkoxy(or Silyloxy)-cyclohexanones.
- 奨励賞受賞 佐野茂樹氏の業績
- 史跡の地, 韓国・慶州でホットな討論会
- New Reaction Mode of the Dieckmann-Type Cyclization under the Lewis Acid-Et_3N Conditions
- Remarkable Effect of D-Sorbitol on the Second Stage in the PLE-Catalyzed Hydrolyses of a σ-Symmetric Diester, cis-Cyclohex-4-ene-1,2-bis(methyl acetate)
- Diazidation of Allylsilanes with a Combination of Iodosylbenzene and Trimethylsilyl Azide, and Synthesis of Ally Azides.
- Novel Deconjugative Esterification of 2-Cyclohexylideneacetic Acids through 4-(Pyrrolidin-1-yl)pyridine-catalyzed Carbodiimide Couplings
- 有機化学反応や物性を発想源とする創薬研究
- Oxidative Grob Fragmentation of γ-Tributylstannyl Alcohols with a Combination of Iodosylbenzene, Dicyclohexylcarbodiimide, and Boron Trifluoride.
- Effect of Silica Gel on the Benzenesulfinic Acid Catalyzed Isomerization of Vinylsilanes. : Formation of Silyl Benzenesulfinate.
- 学術貢献賞受賞難波恒雄氏の業績
- レチノイドによるアルツハイマー病の治療へむけて
- Different Mechanisms of Action of Long Chain Fatty Acid Esters of Podophyllotoxin and Esters of Epipodophyllotoxin against P388 Lymphocytic Leukemia in Mice.
- Generation of [β-(Phenylsulfonyl)alkylidene]carbenes from Hypervalent Alkenyl- and Alkynyliodonium Tetrafluoroborates and Synthesis of 1-(Phenylsulfonyl)cyclopentenes.
- Biomimetic, Chemical, and Spectroscopic Evaluations for the Radiosensitizing Potential of N1- and N2-Substituted Derivatives of 3-Nitro-1,2,4-triazole Toward Hypoxic Cells in the Radiotherapy : Remarkably Different Substituti
- Synthesis of Chiral Hypervalent Organoiodinanes, Iodo(III)binaphthyls, and Evidence for Pseudorotation of Iodine.
- Synthesis of Ethynyl(phenyl)iodonium Tetrafluoroborate. : A New Reagent for Ethynylation of 1,3-Dicarbonyl Compounds.
- Conjugate Addition of Acyloxy Groups to Alkynylphenyliodonium Tetrafluoroborates under Both Basic and Acidic Conditions. : Synthesis of α-Acyloxy Ketones.
- Improved Synthesis of an Energetic Material,1,1,3-Trinitroazetidine Exploiting 1-Azabicyclo[1.1.0]butane
- ヘテロ環を有機合成に使う : ダイナミックヘテロ環化学
- Stabilizing 1,3-Diaxial Interaction between a Metal (Group 14) and a Heteroatom. : Fixation of Six-Membered Carbocycles to the 1,3-Diaxial Conformer.
- Synthesis of Iodo(III) Enol Lactones via Iodine(III)-Induced Lactonization of Alkynoic Acids. : Structurally Potential Serine Protease Inactivators.
- Deconjugative Esterification of 2-(4-Phenylcyclohexylidene)acetic Acid via Intramolecular Chirality Transfer
- A Microwave-assisted Deconjugative Esterification of α,β-Unsaturated Carboxylic Acids through α,β-Unsaturated Ketene Intermediates