<Abstract of annual report>New General Asymmetric Synthesis of Versatile γ-Alkylated Butenolides and Its Application to Expeditious Synthesis of the Chiral Geissman-Waiss Lactones Useful for (+)-Retronecine Synthesis.
スポンサーリンク
概要
著者
-
Shiro M
Rigaku Corp. Tokyo
-
長尾 善光
徳島大学薬学部
-
Shiro M
Rigaku Corporation
-
Ochiai Masahito
Institute For Chemical Research Kyoto University
関連論文
- An Alkoxide-Bridged Dinuclear Zinc(II) Hexaazacryptate : A Novel Phosphate Capture Molecule in Aqueous Solution
- RADIOSENSITIZING HYPOXIC CELLS WITH NEW 3-NITRO-1,2,4-TRIAZOLE DERIVATIVES IN VITRO AND IN VIVO
- Intramolecular Nonbonded S…N Interaction in Rabeprazole
- Synthesis of New Quinolone Antibiotics Utilizing Azetidine Derivatives Obtained from 1-Azabicyclo[1.1.0]butane
- Effects of Magnesium Salts and Amines on the Stereoselectivity in the Imine Aldol Reaction
- Mechanistic Considerations for the Consecutive Cyclization of 2,3-Dibromopropylamine Hydrobromide Giving a Strained Molecule, 1-Azabicyclo[1.1.0]butane
- Synthesis of New Chiral Sulfinyldiacetic Acid Derivatives and Attempt at Chemoselective Asymmetric Pummerer Reaction
- The budget of dissolved trace metals in Lake Biwa, Japan
- Absolute Configuration of Migrastatin, a Novel 14-Membered Ring Macrolide
- Lactonamycin, a New Antimicrobial Antibiotic Produced by Streptomyces rishiriensis MJ773-88K4 II. Structure Determination
- Isolation from Streptomyces of a Novel Naphthoquinone Compound, Naphthablin, That Inhibits Abl Oncogene Functions
- Radiosensitizing Hypoxic Cells with New 3-Nitro-1,2,4-triazole Derivatives In Vitro and In Vivo.
- SYNTHETIC DEVELOPMENT OF HYPOXIC CELL SENSITIZERS HAVING 3-NITROTRIAZOLE MOIETY
- 赤外線蛍光内視鏡の原理と臨床応用
- 2,5-Bis(1', 3'-dithiol-2'-ylidene)-1, 3, 4, 6-tetrathiapentalene and its Related Unsymmetrical Donors
- Preparation, Crystal Structure and Electrical Properties of 2-Cyclopentanylidene-1,3-dithiolo[4,5-d]tetrathiafulvalene Derivatives
- Methylthio Substituted 2,5-Bis(1',3'-dithiol-2'-ylidene)-1,3,4,6-tetrathiapentalene. A Bis-Fused Tetrathiafulvalene
- Diastereoselective Alkylation of Chiral Tin(II) Enolates onto Cyclic Acyl Iminium Ions. : Asymmetric Total Syuthesis of (-)-Supinidine.
- Highly Diastereoselective Alkylation of Chiral Tin(II) Enolates onto Cyclic Acyl Imines, An Efficient Asymmetric Synthesis of Bicyclic Alkaloids Bearing a Nitrogen Atom Ring Juncture.
- New General Asymmetric Synthesis of Versatile γ-Alkylated Butenolides and Its Application to Expeditious Synthesis of the Chiral Geissman-Waiss Lactones Useful for (+)-Retronecine Synthesis.
- PB17 SYNTHETIC STUDIES ON BICYCLIC ALKALOIDS BASED ON A NEW CHIRAL DESIGN UTILIZING VERSATILE MALALDEHYDIC ACID
- A Stable Crystalline (Alkylperoxy)iodinane : 1-(tert-Butylperoxy)-1,2-benziodoxol-3(1H)-one.
- 21世紀のメディシナルケミスト
- Differential Contribution of Metal Complexation and Dimerization to the Chemotherapeutic Potential of Bicyclen-Zn^_2 Complex against Human Immunodeficiency Virus
- A Versatile Macrocyclic [12]aneN_3 for Interconversion of Tetrahedral and Trigonal Bipyramidal Zinc(II) Complexes. Relevance to Four-【double half arrows】 Five-Coordinate Geometries of Zinc(II) in Carbonic Anhydrase
- Synthesis and some properties of phosphoimino-1-azaazulene derivatives
- Expeditious Syntheses of Conjugated Allenyl Esters and Oxazoles through a Cascade Reaction of α-Alkynyl Malonates under Alkaline Conditions
- Enzymatic Hydrolyses of the σ-Symmetric Dicarboxylic Diesters Bearning a Sulfinyl Group as the Prochiral Center
- P-33 α置換セリン誘導体の不斉合成を基盤とする(+)-ラクタシスチンの不斉全合成研究(ポスター発表の部)
- A New Convenient Synthesis of α-Pyrone and α-Pyridone Derivatives
- Expeditious Asymmetric Synthesis of Optically Pure δ-Lactones Bearing Consecutive Three Asymmetric Centers
- Axial Preference of Bulky Group- and Electron-Withdrawing Group-Substituted Oxygen Atom on the Chair-Type Cyclohexanone, Glutaric Anhydride, and Glutarimide.
- Synthesis, Structure, and Self-Oxidation of Alkynyl(phenyl)iodonium Periodates.
- A Facile Synthesis of Novel Chiral Phosphonoacetates Bearing a Stereogenic Phosphorus Atom
- A Facile Method for the Stereoselective Horner-Wadsworth-Emmons Reaction of Aryl Alkyl Ketones
- Synthesis and Antibacterial Activity of New 1β-Methylcarbapenems Having the Potential for Intramolecular Nonbonded S・・・O Interactions
- New Six- to Eight-Membered-Ring Formation Based on the Intramolecular Endo- Mode Ring Closure of Allenyl (Substituted Phenyl)alkyl Ketones
- Characterization of the Sulfonic Esters Adopting a Folded Conformation with Stacked Aromatic Moieties
- Characterization of suspended solids in Lake Biwa by measuring their elemental composition of Al, Si, P, S, K, Ca, Ti, Mn, and Fe
- Stereoselective Synthesis of Tetrasubstituted (Z)-Alkenes from Aryl Alkyl Ketones Utilizing the Horner-Wadsworth-Emmons Reaction
- Effects of the substances secreted from Closterium aciculare (Charophyceae, Chlorophyta) on the growth of freshwater phytoplankton under iron-deficient conditions
- Determination of Minor and Trace Elements in Biogenic Carbonate Minerals of Coccolithophores by High-Resolution Inductively Coupled Plasma Mass Spectrometry
- The possibility of regulating the species composition of marine phytoplankton using organically complexed iron
- A New Type of Inclusion Compounds Composed of a Charge-Transfer Complex between Tetrakis(phenylethynyl)ethene and 2,4,7-Trinitrofluorenone
- Preparation and Crystal Structure of a Parent l-Arylbenzo〔b〕thiophenium Triflate and Its Derivatives
- Efficient Synthesis of Isothiocyanates Based on the Tandem Staudinger/aza-Wittig Reactions and Mechanistic Consideration of the Tandem Reactions
- A Practical and Facile Synthesis of Azetidine Derivatives for Oral Carbapenem, L-084
- Syntheses and Pharmacokinetic Studies of Prodrug Esters for the Development of Oral Carbapenem, L-084
- Facile synthesis of (2-Benzimidazolyl)-1-azaazulenes, (2-Benzothiazolyl)-1-azaazulenes, and related compounds and evaluation of their anticancer in vitro activity
- Facile synthesis of (2-benzimidazolyl)-1-azaazulenes, (2-benzothiazolyl)-1-azaazulenes, and related compouds and evaluation of their anticancer in vitro activity
- Synthesis of Aryl Conjugated (1-Azaazulenyl)acetylenes and Facile Synthesis of Thiophene Fused 1-Azaazulenes
- Dibridged Bis(Zn^-cyclen) : A Novel Host Molecule of Malonate Dianion in Aqueous Solution
- X-Ray Crystal Structures and Chemical Properties of Heterocyclic Azo Compounds Coupled with m-Alkoxyphenols
- On the Mechanism of Stereoisomerization of Methyl Groups of 1,3-Diaxial[cis-3-Benzyloxy)cyclohexyl]chlorodimethylstannane.
- 分子構造特性を基盤とする新反応の開発並びに薬学的応用研究
- Molecular Design and Crystal Structures of Chiral Macrotricyclic Cage Amines
- Facile Synthesis of Optically Active Tertiary Alcohol Building Blocks by Stereospecific C-H Insertion Reaction of Dichlorocarbene with Secondary Alcohol Derivatives.
- Asymmetric Synthesis of (+)-Dihydrokawain-5-ol.
- Facile Synthesis of Optically Active Tertiary Alcohol Building Blocks by Stereospecific C - H Insertion Reaction of Dichlorocarbene with Secondary Alcohol Derivatives
- The Synthesis, Molecular Structure and Selectivity of Macrotricyclic Ammonium-ion Receptor for Bromide Ion
- A highly asymmetric, Lewis Acid-catalysed Diels-Alder reaction using optically active 2-(3-tolyl-p-sulfinyl)furyl α, β-unsaturated ketones as a dienophile.
- Stereoselective Reduction of Chiral 3-(p-Tolylsulfinyl)-2-thienyl Ketones. : A Facile Entry to Optically Active Thienylcarbinols.
- Highly Stereoselective Hetero Diels-Alder Reactions of Chiral 3-(p-Tolylsulfinyl)-2-furaldehyde with Danishefsky's Diene Promoted by a Lanthanoid Lewis Acid.
- Stereoselective Reduction of Chiral 3-(p-Tolylsulfinyl)-2-thienyl Ketones. A Facile Entry to Optically Active Thienylcarbinols
- Diastereoselective Allylation of Chiral Sulfinyl-substituted Thiophenecarbaldehydes with a Lewis Acid.
- Nucleophilic Substituion Reaction of Optically Pure Chloroselenurane with Active Methylene Compounds. : Formation of Optically Pure Selenonium Ylides.
- Optically Pure Haloselenuranes. : First Synthesis and Nucleophilic Substitutions.
- Diels-Alder Reactions of Optically Active α-(2-exo-Hydroxy-10-bornylsulfinyl)-maleimides and its Application to Optically Active 5-Functionalised Pyrrolidines via Retro-Diels-Alder Reaction.
- Nucleophilic Substitution Reaction of Optically Pure Chloroselenurane with Active Methylene Compounds. Formation of Optically Pure Selenonium Ylides
- Total Synthesis of (+)-Asperlin Starting with (S, S)-Tartaric Acid.
- Total Synthesis of (+)-Asperlin Starting with (S,S)-Tartaric Acid
- Asymmetric Diels-Alder Cycloaddition with Chiral 2-Alkylsulfinyl-1-nitroalkenes.
- Addition-Elimination Strategy for Asymmetric Induction : A Chiral Sulfoxide as a Leaving Group.
- Cyclization, Ring-Expansion, and Several Cascade Reactions Utilizing Allenylic Molecular Structure Characteristics
- 現状のままで満足ですか年輩者 : 今や集学的に"熟学"事始めの時
- 薬学教育における現行の問題点と21世紀への展望(21世紀の人づくり)(21世紀:薬学の時代へ)
- α-置換セリン誘導体の不斉合成
- 技術賞受賞抗血小板剤シロスタゾールの研究開発
- Generalization, Alteration, and Enhancement of the Stereoselectivity in the Cieplak-Mode Reductions of 4-Alkoxy(or Silyloxy)-cyclohexanones.
- 奨励賞受賞 佐野茂樹氏の業績
- 史跡の地, 韓国・慶州でホットな討論会
- New Reaction Mode of the Dieckmann-Type Cyclization under the Lewis Acid-Et_3N Conditions
- Remarkable Effect of D-Sorbitol on the Second Stage in the PLE-Catalyzed Hydrolyses of a σ-Symmetric Diester, cis-Cyclohex-4-ene-1,2-bis(methyl acetate)
- Diazidation of Allylsilanes with a Combination of Iodosylbenzene and Trimethylsilyl Azide, and Synthesis of Ally Azides.
- 有機化学反応や物性を発想源とする創薬研究
- Oxidative Grob Fragmentation of γ-Tributylstannyl Alcohols with a Combination of Iodosylbenzene, Dicyclohexylcarbodiimide, and Boron Trifluoride.
- Effect of Silica Gel on the Benzenesulfinic Acid Catalyzed Isomerization of Vinylsilanes. : Formation of Silyl Benzenesulfinate.
- α-Versus β-Elimination of (Z)-(β-Halovinyl)iododinium Salts : Generation of(α-Alkylidene)carbenes and Their Facile Intramolecular 1,2-Migration
- Ion transfer at the interface between an aqueous solution in the presence of concentrated salts and an organic solution studied by polarography at the electrolyte solution dropping electrode
- Different Mechanisms of Action of Long Chain Fatty Acid Esters of Podophyllotoxin and Esters of Epipodophyllotoxin against P388 Lymphocytic Leukemia in Mice.
- Generation of [β-(Phenylsulfonyl)alkylidene]carbenes from Hypervalent Alkenyl- and Alkynyliodonium Tetrafluoroborates and Synthesis of 1-(Phenylsulfonyl)cyclopentenes.
- Biomimetic, Chemical, and Spectroscopic Evaluations for the Radiosensitizing Potential of N1- and N2-Substituted Derivatives of 3-Nitro-1,2,4-triazole Toward Hypoxic Cells in the Radiotherapy : Remarkably Different Substituti
- Synthesis of Chiral Hypervalent Organoiodinanes, Iodo(III)binaphthyls, and Evidence for Pseudorotation of Iodine.
- Synthesis of Ethynyl(phenyl)iodonium Tetrafluoroborate. : A New Reagent for Ethynylation of 1,3-Dicarbonyl Compounds.
- Conjugate Addition of Acyloxy Groups to Alkynylphenyliodonium Tetrafluoroborates under Both Basic and Acidic Conditions. : Synthesis of α-Acyloxy Ketones.
- Improved Synthesis of an Energetic Material,1,1,3-Trinitroazetidine Exploiting 1-Azabicyclo[1.1.0]butane
- Optically Active Cobalt(III) Complexes Containing Partial Cubane Co_3O_4 Core: Syntheses and Structures of the Isomers of [Co_3(L)_3(μ-OH)_3(μ_3-O)]Cl (L = Ethylenediamine-N-acetate)
- ヘテロ環を有機合成に使う : ダイナミックヘテロ環化学
- Stabilizing 1,3-Diaxial Interaction between a Metal (Group 14) and a Heteroatom. : Fixation of Six-Membered Carbocycles to the 1,3-Diaxial Conformer.
- Synthesis of Iodo(III) Enol Lactones via Iodine(III)-Induced Lactonization of Alkynoic Acids. : Structurally Potential Serine Protease Inactivators.