High Sensitivity InSb Hall Effect Biosensor Platform for DNA Detection and Biomolecular Recognition Using Functionalized Magnetic Nanobeads
スポンサーリンク
概要
- 論文の詳細を見る
A compact, high sensitivity and low cost biosensing platform based on InSb thin film micro-Hall effect biosensors [$30 \times 30$ μm2; magnetic field sensitivity of 1.8 nT/(Hz)1/2] was developed and used for the detection of DNA molecules labeled with magnetic beads. Magnetic beads (${\sim}200$ nm diameter) were functionalized and selectively immobilized onto Hall biosensor surfaces via highly specific hybridization of complementary oligonucleotides and subsequently detected by magnetic susceptibility measurements. The potential for parallel biomolecular analysis with $5 \times 5$ μm2 linear sensor arrays was demonstrated.
- Japan Society of Applied Physicsの論文
- 2005-11-10
著者
-
Togawa Kiyoshi
Department Of Cardiology Surugadai Nihon University Hospital
-
Sandhu Adarsh
Department Of Electrical And Electronic Engineering Tokai University
-
NARIMATSU Hiroki
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
-
NISHIO Kousuke
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
-
Abe Masanori
Department Of Anesthesiology Faculty Of Medicine University Of The Ryukyus
-
Sanbonsugi Hideaki
Department Of Electrical Engineering Tokyo Institute Of Technology
-
Handa Hiroshi
Graduate School Of Bioscience And Biotechnology And Frontier Collaborative Research Center Tokyo Ins
-
Narimatsu Hiroki
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan
-
Handa Hiroshi
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan
-
Nishio Kousuke
Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan
-
Sandhu Adarsh
Department of Electrical and Electronic Engineering, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8552, Japan
-
Abe Masanori
Department of Physical Electronics, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8552, Japan
-
Togawa Kiyoshi
Department of Electrical and Electronic Engineering, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8552, Japan
-
Sanbonsugi Hideaki
Department of Physical Electronics, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8552, Japan
関連論文
- PJ-076 Plasma Epinephrine and Epinephrine/norepinephrine Ratio During Head-up Tilt Test Decrease with Aging in Patients with Neurally Mediated Syncope(Autonomic nervous system-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-075 Cardioinhibitory Component of Neurally Mediated Syncope is Decreased with Aging(Autonomic nervous system-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-187 The Usefulness of Combination Therapy with Bepridil and Class 1c Anti-arrhythmic Drug on Pharmacological Defibrillation of Persistent Atrial Fibrillation(Arrhythmia, therapy-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society
- OJ-205 The Focal Ablation of Atrial Flutter after Linear Ablation of Cavotricupid Isthmus(Arrhythmia, therapy-4 (A) OJ35,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Cilostazol Prevent the Recurrence of Atrial Fibrillation after Cavo-tricuspid Isthmus Ablation in Patients with Sinus Node Dysfunction (Arrhythmia, Pharmacological Therapy 6 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Noninvasive Evaluation of the Pharmacological Therapy for Patients with Sino-Atrial Nodal Dysfunction (ECG/Body Surface Potential Mapping/Holter 6 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-453 The long-term effect of cilostazol in patients with sino-atrial nodal dysfunction(Arrhythmia, Pharmacological Therapy 5 (A) : OJ55)(Oral Presentation (Japanese))
- Effect of CdCl_2 Treatment Conditions and Stoichiometry on The Deep Level, Carrier Lifetime and Converstion Efficiency of CdTe Thin Film Solar Cells
- Alcohol Consumption Is Associated with Decreased Insulin Resistance Independent of Body Mass Index in Japanese Community-Dwelling Men
- Delayed response of transcranial myogenic motor-evoked potential monitoring to spinal cord ischemia during repair surgery for descending thoracic aortic aneurysm
- OE-414 How TNFα Receptor Polyorphism Affect the State of Kawasaki Disease?(Congenital heart disease/Kawasaki's disease(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease
- The Role of the Low-Amplitude Potential in the Initial Signal-Averaged P Wave Electrogram in the Sick Sinus Syndrome
- Alcohol-induced neurally mediated syncope : characteristics in humoral responses during headup tilt
- Localization of Sinus Nodal Impulset : Sinus Node Electrograms Mapping Guided by Intracardiac Echocardiography
- Edaravone, a Potent Free Radical Scavenger, Prevents Anthracycline-Induced Myocardial Cell Death
- Ferrite Plating of Fe_3O_4 Films on Expanded Polytetrafluoroethylene Modified by Xe Excimer Lamp
- Ferrite Plating of Ba-Containing Iron Oxide Films Using Chelated Highly Alkaline (pH=11-13) Aqueous Solutions
- Preparation of Co_xFe_O_4 Films in Aqueous Solution at 120-200℃ by "Hydrothermal Ferrite Plating"
- Engineering immune therapy against hepatitis B virus
- Aberrant halt of syringe pump motion : an improved system to prevent false setting of the syringe
- Fabrication of AlN/Al_2O_3 GHz Band SAW Filter and Simulation Analysis
- クラスタービーム法によるGeナノ構造薄膜のラマン分光評価
- The influence of sleep position and obesity on sleep apnea
- Influence of alcohol on respiratory disturbance during sleep
- Evaluation of the auto continuous positive airway pressure efficacy by upper airway pressure measurement
- Intensity of snoring in patients with sleep-related breathing disorders
- Effectiveness of prosthetic mandibular advancement for obstructive sleep apnea : Analysis by sleep position
- Effectiveness of tonsillectomy in adult sleep apnea syndrome
- High Sensitivity InSb Hall Effect Biosensor Platform for DNA Detection and Biomolecular Recognition Using Functionalized Magnetic Nanobeads
- Properties of High Quality InP Epilayers Grown by Solid Source Molecular Beam Epitaxy using Polycrystalline GaP as a Phosphorous Source
- Exploring the Usefulness of Monitoring EEG Activity as a Means of Enhancing Athletic Performance : Study of Technological Requirements for the Remote and Real Time Measurement of EEG Activity of Athletes
- InGaP/lnGaAs/GaAs High Electron Mobility Transistor Strutcture Grown by Solid Source Molecular Beam Epitaxy Using GaP as Phosphorous Source
- Direct Magnetic Imaging of Ferromagnetic Domain Structures by Room Temperature Scanning Hall Probe Microscopy Using a Bismuth Micro-Hall Probe : Surfaces, Interfaces, and Films
- EFFICACY OF LAPAROSCOPIC RADIOFREQUENCY ABLATION FOR HEPATOCELLULAR CARCINOMA COMPARED TO PERCUTANEOUS RADIOFREQUENCY ABLATION WITH ARTIFICIAL ASCITES
- Neuropsychiatric dysfunction in patients with chronic hepatitis and liver cirrhosis
- LAPAROSCOPIC FEATURES AND INTEROBSERVER VARIATION OF HISTOLOGICAL DIAGNOSIS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE
- Clinical usefulness of quantitative evaluation of visceral fat by ultrasonography
- Clinical features of symptomatic primary biliary cirrhosis initially complicated with esophageal varices
- Clinical characteristics of autoimmune hepatitis in older aged patients
- Diastereoselective Synthesis of β-Amino Esters by the Lewis Acid-Mediated Reaction of N-Tosyl Aldimines with Ketane Bis(trimethylsilyl) Acetals
- Direct Detection of Redox Reactions of Sulfur-containing Compounds on Ferrite Nanoparticle (FP) Surface
- Anomalous Magneto-Optic Kerr Effect in Ordered Perovskites A_2FeMoO_6 (A=Ba, Sr, Ca)
- Magneto-Optical Properties of Magnetoplumbites BaFe_O_, SrFe_Al_xO_ and PbFe_O_
- Signal-to-Noise Ratio in Polarization Modulation Method for Magneto-Optical Measurement
- Magneto-Optic Kerr Effect in RF Sputtered Co-Cr Film with Perpendicular Anisotropy
- Anomalous Magneto-Optical Kerr Rotation in Sr_2FeMoO_6
- Anomalous Decrease of the Spontaneous Magnetization of YFe_CO_x/2Ti_x/2O_3 in the Spin Reorientation Region
- A Method for Measuring the Direction Angle of a Magnetization with a Vibrating Sample Magnetometer : Application to SmFeO_3 in the Spin Reorientation Region
- Ferromagnetic (LaSr)MnO_3 Films Deposited by RF Sputtering
- Film Thickness Allowance and Waveguide Length in 3-Layer Unidirectional Magneto-Optical TE-TM Mode Converter
- A New Magneto-Optic Readout Technique with High Speed and High Sensitivity
- Bistable Optical Device Using the Electrostrictive Displacement Transducer
- X-Ray and Mossbauer Studies of Ba_3FeTa_2O_9 and Sr_3FeTa_2O_9
- Faraday Rotation and Birefringence of Fe_3BO_6
- A Reflection Method of Determining Birefringence and Refractive Index in Orthorhombic Crystal
- Anisotropy of the Faraday Rotation in the Orthoferrites SmFeO_3 and YFe_Co_Ti_O_3
- Magnetostriction of SmFeO_3 and YFe_Co_Ti_O_3 in the Spin Reorientation Region
- Dependence of Dichroism in SmFeO_3 on Crystal Growth Technique and Hydrogen Heat Treatment
- Magnetic and Mossbauer Studies of a New Compound YFe_2O_4
- Magneto-Optical Effect and Effective Dielectric Tensor in Composite Material Containing Magnetic Fine Particles or Thin Layers
- Giant Faraday Rotation of Ce-Substituted YIG Films Epitaxially Grown by RF Sputtering : Magnetism, Magnetic Materials and Devices
- Enhancement of Faraday Effect in Highly Ce-Substituted YIG Epitaxial Films by RF Sputtering
- Influence of Tunneling on Electron Screening in Low Energy Nuclear Reactions
- Liver/spleen volume ratio as a predictor of prognosis in primary biliary cirrhosis
- Synthesis of yttrium iron garnet nanoparticles by sol-gel method
- A Method of Measuring Faraday Rotation and Dichroism in Orthoferrite
- A Simple Method for the Measurement of Intrinsic Faraday Rotation and Birefringence in Orthoferrite
- Amino acid imbalance in patients with chronic liver diseases
- Usefulness of the hyperechoic rim for assessing the therapeutic efficacy of radiofrequency ablation in hepatocellular carcinoma patients
- Early biochemical response to ursodeoxycholic acid predicts symptom development in patients with asymptomatic primary biliary cirrhosis
- Mossbauer Study in Spinel Fe_2MoO_4
- X-Ray and Mossbauer Studies of the Oxygen-Deficient SrFe_xMo_O_
- X-Ray and Neutron Diffraction Studies in Spinel Fe_2MoO_4
- Compensation Temperature of Spontaneous Magnetization in Spinel Fe_2MoO_4
- Natural history of primary biliary cirrhosis
- Hepatocellular Carcinoma in a Case of Wilsons Disease Treated with Radiofrequency Ablation Therapy
- PJ-732 The New Concept of Hemodialysis to Prevent Contrast-Induced Nephropathy in a Porcine Model(PJ123,Kidney/Renal Circulation/CKD 6 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Planar Microfluidic System Based on Electrophoresis for Detection of 130-nm Magnetic Labels for Biosensing
- TEM Observations of Magnetic Domains and Grain Boundaries on Spin-sprayed Ferrite Films Exhibiting High Permeability Usable for Gigahertz Noise Suppressors
- Novel Type of Conducted Noise Suppressor in GHz Range Using Ferrite-plated Film
- Mossbauer Study of FeMo_2S_4
- Mossbauer Study on Pb(FeTa)_O_3
- Thermal Dilatation in Pb(Zn_1/3Nb_2/3)O_3 Crystal
- Critical Divergence of the HF Magnetic Susceptibility of SmFeO_3 in the Spin Reorientation Temperature Region
- Right coronary artery spasms triggered by mechanical compression during off-pump coronary artery bypass grafting surgery
- Thermal Diffusivity and Seebeck Coefficient of Semiconducting KTaO_3
- Changes of anthropometric and biological parameters in patients with non-alcoholic steatohepatitis for dietary modification
- Magnetic and Mossbauer Studies of the Ordered Perovskites Sr_2Fe_Re_O_6
- A Digital Ellipsometer
- CONGENITAL HEPATIC FIBROSIS WITHOUT ANY SYMPTOMS AS DIAGNOSED BY LAPAROSCOPY
- Maskless Patterning of Ferrite Film by Selected Area Film Growth in Aqueous Solution by "Laser-Enhanced Ferrite Plating"
- High-Rate Deposition of Ferrite Films in Aqueous Solution by Light-Enhanced Ferrite Plating
- Ferrite Plating of (Fe, Ni, Zn) _3O_4 Films in Aqueous Solution by an "Improved" Spray-Spin-Coating Method : Chemistry (incl. physical process)
- Ferrite-Plating in Aqueous Solution : A New Method for Preparing Magnetic Thin Film
- Ultrasonic Visualization of Still and Flowing Waters Using Contrast Agents of Magnetite-Encapsulated Porous Silica Microspheres
- Microstructure of Bi_Y_Fe_5O_ Films Made by Pyrolysis : Magnetism, Magnetic Materials and Devices
- Layer-by-Layer Assembled Transparent Conductive Graphene Films for Silicon Thin-Film Solar Cells
- Room Temperature Sub-Micron Magnetic Imaging by Scanning Hall Probe Microscopy
- High Sensitivity InSb Hall Effect Biosensor Platform for DNA Detection and Biomolecular Recognition Using Functionalized Magnetic Nanobeads