Long-Term Comparison of Apical Versus Asymmetric Hypertrophic Cardiomyopathy
スポンサーリンク
概要
- 論文の詳細を見る
Although apical hypertrophic cardiomyopathy (HCM) has been considered to be more benign than asymmetric HCM, few studies have directly compared their clinical features. We compared the electrocardiographic data and longterm outcomes between patients with apical HCM versus asymmetric HCM. This retrospective study enrolled 796 patients (243 apical HCM and 553 asymmetric HCM). We assessed long-term all-cause and cardiac mortalities using an inverse probability of treatment weighted (IPTW) method and propensity score matched (PSM) analysis. In patients with asymmetric HCM, QT prolongation, QRS widening, PR prolongation, and pathologic Q wave were significantly more frequent. The incidences of early repolarization were similar (11% in apical and 12% in asymmetric HCM, <I>P</I> = 0.19). The median follow-up duration was 6.5 years. There was a borderline significant difference in overall survival rates between the apical and asymmetric HCM groups (73% versus 69%, log rank <I>P</I> = 0.38, IPTW: <I>P</I> = 0.05, PSM: <I>P</I> = 0.05). Regarding cardiac death, asymmetric HCM was more hazardous than apical HCM (89% versus 77%, log rank <I>P</I> = 0.04, IPTW: <I>P</I> = 0.03, PSM: <I>P</I> = 0.03). There was no electrocardiographic predictor for the long-term outcomes, although beta-blocker use was significantly associated with lower overall death (HR = 0.58, 95% CI = 0.41-0.81) and slightly lower cardiac death (HR = 0.86, 95% CI = 0.55-1.33). The overall survival rate of apical HCM was as high as that of asymmetric HCM, but the cardiac survival rate was significantly lower in patients with asymmetric HCM. Beta-blocker use was associated with better long-term outcomes.
著者
-
Kim Dae
Department Of Anatomy And Center For Advanced Medical Education By Bk21 Project Inha University Coll
-
Hwang Ki
Department Of Orthopaedic Surgery Spine Service Maimonides Medical Center
-
Kim Cheol-ho
Department Of Biological Sciences College Of Natural Science Sungkyunkwan University
-
Nam Gi-byoung
Department Of Internal Medicine Asan Medical Center University Of Ulsan College Of Medicine
-
Choi Kee-joon
Department Of Internal Medicine Asan Medical Center University Of Ulsan College Of Medicine
-
HAN Seungbong
Department of Biostatistics and Clinical Epidemiology, Asan Medical Center, University of Ulsan College of Medicine
-
Song Jong-Min
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Kim Sung-Hwan
Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea
-
Kim You-Ho
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Kim Cheol-Ho
Department of Internal Medicine, Seoul National University College of Medicine, Bundang Hospital
-
Kang Duk-Hyun
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Kim Seon-Ok
Department of Biostatistics, University of Ulsan College of Medicine, Asan Medical Center
-
Lee Cheol-Whan
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Song Jae-Kwan
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Hwang Ki
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Nam Gi-Byoung
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Choi Kee-Joon
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
-
Kim Dae
Department of Cardiology, University of Ulsan College of Medicine, Asan Medical Center
関連論文
- Relationship Between Multiple Plasma Biomarkers and Vulnerable Plaque Determined by Virtual Histology Intravascular Ultrasound
- Adult Scoliosis : Prevalence, SF-36, and Nutritional Parameters in an Elderly Volunteer Population
- Optimal treatment of hypertension in the elderly : A Korean perspective
- Association Between Blood Pressure Variability and Inflammatory Marker in Hypertensive Patients
- Current Status and Characteristics of Hypertension Control in Community Resident Elderly Korean People : Data from a Korean Longitudinal Study on Health and Aging (KLoSHa Study)
- Proteomic Analysis of Bronchoalveolar Lavage Fluid Obtained from Rats Exposed to Formaldehyde
- 1,2,3,4,6-Penta-O-galloyl-β-D-glucose Protects Splenocytes against Radiation-Induced Apoptosis in Murine Splenocytes
- Musculature of the Pars Marginalis of the Upper Orbicularis Oris Muscle
- Location and Nature of Retro-Orbicularis Oculus Fat and Suborbicularis Oculi Fat
- Relation of Mental Nerve With Mandibular Branch of the Facial Nerve
- 0097 International Session Reperfusion Injury does not Induce Apoptosis in Rat Myocardium
- 近位尿細管細胞におけるグルココルチコイドによる分極性膜性輸送の制御機構 : Ca^の関与
- Predictive Value of C-Reactive Protein for Major Postoperative Complications Following Off-Pump Coronary Artery Bypass Surgery : Prospective and Observational Trial
- Epithelial-mesenchymal transition gene signature to predict clinical outcome of hepatocellular carcinoma
- Bulk Heterojunction Organic Photovoltaic Cell Fabricated with a p-Type Conjugated Star-shaped Molecule
- Effect of Hypercholesterolemia on Macrophage Infiltration After Balloon Injury to Rabbit Iliac Artery
- Purification and Characterization of a Novel Fibrinolytic Enzyme from Bacillus sp. KA38 Originated from Fermented Fish
- Postoperative Radiotherapy in Carcinoma of the Cervix with Microscopically Positive Resection Margin
- Adrenocortical oncocytoma displaying intense activity on ^F-FDG-PET : a case report and a literature review
- Annealing Effect and Measurement of Magnetostriction in Fe_Co_V_2 Alloy using the Michelson Laser Interferometer
- Differential effects and changes of ceruloplasmin in the hippocampal CA1 region between adult and aged gerbils after transient cerebral ischemia
- Effects of Antiarrhythmic Drugs on Inappropriate Shocks in Patients With Implantable Cardioverter Defibrillators
- Clinical Characteristics of Brugada Syndrome in a Korean Population
- Altered GABA_B receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity
- P-IS-26 Proportion of peripheral blood CD4+CD25high regulatory T cells in patients with gynecologic cancers(Oncology 7,Group 94,International Session)
- Comparative study of laparoscopic radical hysterectomy and radical abdominal hysterectomy in patients with FIGO stage IB cervical cancer(Oncology 9)
- Identification and characterization of potential serum marker, Haptoglobin-α and -β subunits, in ovarian cancer(Oncology 3)
- An in vivo approach for Arabidopsis as a model system for cell biology focused on intracellular trafficking
- Neuroprotection and Enhancement of Learning and Memory by BF-7
- Erratum: Neuroprotection and Enhancement of Learning and Memory by BF-7[J. Health Sci. 51(3): 317-324 (2005)]
- Clinical Features of Bone Metastases Resulting from Thyroid Cancer : A Review of 28 Patients over a 20-year Period
- Involvement of Oxidized Peroxiredoxin-3 in Cadmium- and Ceramide-induced Apoptosis of Human Neuroblastoma Cells
- A Noise Reduction Method for a Modulated Orthogonal Sequence under Impulsive Noise Environment
- Assessing the Quality of Fuzzy Partitions Using Relative Intersection(Computation and Computational Models)
- Analysis of Correlation between Rectal Complications and Rectal Dose Following High Dose Rate Intracavitary Radiotherapy in Patients with Uterine Cervix Cancer:In vivo Dosimetric Analysis
- Secondary Angiosarcoma Following Irradiation-Case Report and Review of the Literature-
- CURRENT STATUS OF HIGH DOSE RATE BRACHYTHERAPY FOR CERVICAL CANCER IN KOREA
- Hemolytic Streptococcus Preparation OK-432; Benefical Adjuvant Therapy in Recurrent Gastric Carcinoma
- Effects of Oral Administration of Streptococcal Preparation OK-432 on Thoracic Duct Lymphocytes
- Effects of Biological Response Modifier on Thoracic Duct Lymphocytes in Recurrent Gastric Cancer Evaluation of OK-432, a Hemolytic Streptococcus Preparation
- Quantum-Disk Excitons and Their Interaction with Phonons in BiI_3(Condensed Matter : Electronic Structure, Electrical, Magnetic and Optical Properties)
- Tumor Volume Change during Neoadjuvant Chemotherapy in Locally Advanced Cervical Cancer : Predictive Value of Recurrence(Oncology 9)
- NON-SYMMETRIC DIRICHLET FORMS FOR OBLIQUE REFLECTING DIFFUSIONS
- Performance of Single-Electron Transistor Logic Composed of Multi-gate Single-Electron Transistors
- Significance of GLUT1 expression in adenocarcinoma and adenoma of the ampulla of Vater
- A Novel 3-D Network of Fe(II) Glutarate : 2-D Honeycomb-type Edge-shared FeO_6 Layers and Isolated Interlayer FeO_6 Octahedra
- Stress Effect on the Reliability of pMOS TFTs for 16 Mb SRAM:DC Stress at Room and Elevated Temperatures
- Cerebral cortical phospholipase A_2 activity of senescence-accelerated mouse is increased in an age-dependent manner
- Species-Specific Detection of Listeria monocytogenes Using Polymerase Chain Reaction Assays Targeting the prfA Virulence Gene Cluster
- Exciton Transitions in Size-Distributed BiI_3 Microcrystallites Embedded in CdI_2 Crystals
- Oxygen Stability and Leakage Current Properties of La-Modified Bismuth Titanate Ferroelectric Thin Films
- Double Stapling Roux-en-Y Reconstruction in a Laparoscopy-Assisted Distal Gastrectomy
- Multi-Podands. Ag(I) Complexation with Mono - to Quadru-Podands Having Sulfur Donor
- PRODUCTION OF WSSV-FREE Penaeus chinensis LARVAE
- A Design for a New Minimum-Bandwidth Line Code of MB810+
- Experimental Evaluation of a Binary Minimum-Bandwidth Line Code MB34 for High-Speed Optical Transmission
- Is reduced bone mineral density independently associated with coronary artery calcification in subjects older than 50 years?
- Photoelectron Angular Distributions for Photoionization of the Be-like B^+ Ion(Atomic and Molecular Physics)
- Nanoscale Observation of Poling Behaviors in Nd-Substituted Bi4Ti3O12 Ferroelectric Thin Films
- Association between the p22^-930A/G polymorphism and blood pressure in normotensive subjects
- Efficient Algorithms for Computing the Shadow Volumes from an Area Light Source
- Northern Barbados accretionary prism : Structure, deformation, and fluid flow interpreted from 3D seismic and well-log data
- Experimental Evaluation of a Binary Minimum-Bandwidth Line Code MB34 for High-Speed Optical Transmission
- Byte Erasable NOR Flash EEPROM with Double Diffused Drain for High Programming Speed
- Effect of catheter ablation on the left ventricular mass index and other echocardiograph parameters in atrial fibrillation patients : comparison with antiarrhythmic drug treatment
- Metal Node Contact TFT SRAM Cell for High Speed, Low Voltage Applications
- Photothermal Effect and Heat Dissipation in a Micromechanical Resonator
- Roles of AKT1 and AKT2 in non-small cell lung cancer cell survival, growth, and migration
- Layout Dependent Induced Leakage and its Prevention with Different Shallow Trench Isolation Schemes in 0.18 μm Dual Gate Complementary Metal Oxide Semiconductor Technology
- Identification of a 42-kDa Group IV cPLA_2-activating protein, cPLAPγ, as a GTP-binding protein in the bovine brain
- Sustainment of Plasma Density by a Low Magnetic Field in a Dual-Frequency Capacitively Coupled Plasma
- Publisher's Note: ``A New Lateral Trench Electrode Insulated Gate Bipolar Transistor with p+ Diverter for Superior Electrical Characteristics''
- Early recovery of urinary continence after radical prostatectomy : Correlation with vesico-urethral anastomosis location in the pelvic cavity measured by postoperative cystography
- Photothermal Effect and Heat Dissipation in a Micromechanical Resonator
- The effect of cuff pressure on postoperative sore throat after Cobra perilaryngeal airway
- Coronary Sinus Activation Pattern in the Differential Diagnosis of Regular Atrial Tachyarrhythmias During Catheter Ablation of Atrial Fibrillation
- Predicting survival after living and deceased donor liver transplantation in adult patients with acute liver failure
- A New Lateral Trench Electrode Insulated Gate Bipolar Transistor with p+ Diverter for Superior Electrical Characteristics
- Long-Term Comparison of Apical Versus Asymmetric Hypertrophic Cardiomyopathy
- Fiberoptic-guided tracheal tube placement through the air-Q^【○!R】 Intubating Laryngeal Airway : a performance study in a manikin
- Effect of Rice Cell-Derived Human Granulocyte-Macrophage Colony-Stimulating Factor on 5-Fluorouracil-Induced Mucositis in Hamsters
- Coronary Sinus Activation Pattern in the Differential Diagnosis of Regular Atrial Tachyarrhythmias During Catheter Ablation of Atrial Fibrillation
- Efficacy of ^Tc-sestamibi SPECT/CT for minimally invasive parathyroidectomy : comparative study with ^Tc-sestamibi scintigraphy, SPECT, US and CT