魚類におけるクロロフェノ-ル類の代謝に関する研究-1-キンギョによる水中PCPの吸収および排泄〔英文〕

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A study has been made of the absorption and excretion of pentachlorophenol (PCP) by goldfish, Carassius auratus. Three concentrations of PCP (0.1, 0.2 and 0.4ppm) were investigated, and it was found that the amount accumulated by the fish increased with time. The concentration factor after exposure for 120hr in 0.1ppm PCP was approximately 1000. Maximum accumulation was observed in fish exposed to 0.2ppm and showed a value of 116 μg-PCP/g-body weight. PCP absorbed by the fish was rapidly excreted by active elimination. After 10hr in PCP-free water only half of the original amount remained. When fish which had been previ-ously exposed to 14C-labeled PCP were transferred to water containing non-radioactive PCP, both excretion into and accumulation of PCP from the medium were observed, i.e. the con-centration in the fish increased by the amount expected from absorption minus that expected from excretion until it reached a concentration of about 100 μg-PCP/g-body weight at which time mortality occurred. It was also shown that most of the PCP found in the fish had not undergone decmposition.