魚類におけるクロロフェノール類の代謝に関する研究-IV : キンギョによる水中フェノールの吸収および排泄

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A study has been made of the absorption and excretion of phenol by goldfish, Carassius auratus. No fish died in 5-20ppm phenol-media during exposure for 5 days, but the fish which were exposed to 40-100ppm media showed 50% mortality in exposure periods from 20 to 30 hr. Phenol was rapidly absorbed by the fish, showing a concentration factor of 1.2 after 1 hr exposure, but the subsequent increase of phenol in the fish was slower and the factors ranged from 1.2 to 2.3 during exposure for 5 days, although that of PCP was approxi-mately 1000. Maximum accumulation was observed in fish exposed to 100ppm and showed a value of 187μg-phenol/g-body weight. The concentration of phenol found in the dead fish ranged from 68 to 187μg/g, a level comparable to that of PCP in goldfish which died in PCP-media. Phenol absorbed by the fish was so rapidly excreted that the concentration fell to about one-fourth of the initial amount after 1 hr, but the subsequent decrease was slower. The phenol excreted within 1 hr was mostly free-form, but most of that excreted subsequently was some bound-form which was easily hydrolyzed on heating in acidic solution to release free-phenol.
公益社団法人日本水産学会の論文