Effects of Long-Term Administration of Hesperidin and Glucosyl Hesperidin to Spontaneously Hypertensive Rats
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概要
- 論文の詳細を見る
Hesperidin (LIES) is a flavonoid contained in citrus fruit peel. We investigated the effects of long-term administration of HES and its newly developed water soluble analogue, glucosyl hesperidin (GHES), to spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY). Animals were fed with diets containing HES or GHES (30 mg/d/kg body weight) for 25 wk. While the daily food intake and the body weight of administered rats were not different from those of the non-administered control rats in both SHR and WKY through the experimental period, the blood pressure and heart rate of SHR administered HES or GHES for longer than 15 wk decreased as compared to the control group. The blood pressure and heart rate of WKY were not changed by the long-term administration of HES or CHES. These results suggest that HES and GHES have anti-hypertensive effects on hypertensive animals.
- 財団法人 学会誌刊行センターの論文
- 2002-10-01
著者
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KONDO Yasuhiro
Department of Animal Science and Technology, Okayama University Graduate School of Natural Science a
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Abe Asaki
Graduate School Of Natural Science And Technology Okayama University
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Abe Asaki
Department Of Animal Science And Technology Faculty Of Agriculture Okayama University
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Kondo Y
Department Of Animal Science Faculty Of Agriculture Okayama University
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Kondo Y
Okayama Univ. Okayama Jpn
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MITSUZUMI Hitoshi
Hayashibara Biochemical Laboratories, Inc.
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Mitsuzumi Hitoshi
Hayashibara Biochemical Laboratories Inc.
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Ohtsuki Kazumasa
Department Of Animal Science Faculty Of Agriculture Okayama University
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Iwasaki Yoshie
Japan Cytology Research
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KONDO Masaru
Department of Animal Science, Faculty of Agriculture, Okayama University
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UEMURA Kanae
Department of Animal Science, Faculty of Agriculture, Okayama University
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IWASAKI Yumiko
Department of Animal Science, Faculty of Agriculture, Okayama University
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Uemura Kanae
Department Of Animal Science Faculty Of Agriculture Okayama University
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Kondo Masaru
Department Of Animal Science Faculty Of Agriculture Okayama University
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Kondo Yasuhiro
Department Of Animal Science And Technology Okayama University Graduate School Of Natural Science An
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