Effect of Tomato Intake on Striatal Monoamine Level in a Mouse Model of Experimental Parkinson's Disease
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概要
- 論文の詳細を見る
An ingestion of tomato powder rich in lycopene was examined for its effect on mice with Parkinsons disease-like syndrome induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). To assess the preventive effect of tomato against the MPTP-in-duced selective destruction of dopaminergic nigrostrie, we determined striatal dopamine (DA). A4-wk ingestion of the experimental diet containing 20% (w/w) lyophilized tomato powders before MPTP treatment prevented a decrease in the DA level. This suggests that the tomato ingestion might serve as a preventive against neurodegenerative diseases such as Parkinsons disease caused by MPTP and other environmental toxins.
- 財団法人 学会誌刊行センターの論文
- 2002-06-01
著者
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Inakuma T
Kagome Co. Ltd.
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Inakuma Takahiro
Res. Inst. Kagome Co. Ltd.
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HIRANO Takaaki
Research Institute, Kagome Co., Ltd.
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Hirano Takaaki
Research Institute Kagome Co. Ltd.
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Arimoto Yasushi
Research Institute Kagome Co. Ltd.
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Suganuma H
Research Institute Kagome Co. Ltd.
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Suganuma Hiroyuki
Research Institute Kagome Co. Ltd.
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Inakuma Takahiro
Research Institute Kagome Co. Ltd
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Inakuma Takahiro
Research Institute, Kagome Company Ltd.
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