Effect of Dietary Safflower Phospholipid on Plasma and Liver Lipids in Rats Fed a Hypercholesterolemic Diet.

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概要

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• The effect of safflower phospholipid (SP) on plasma and liver lipids in rats fed a hypercholesterolemic diet was examined. Tri-glyceride mixture (SPO) of safflower oil and palm oil (8:2) containing almost comparable amounts of linoleic acid to safflower phospholipid was used as a control diet. Similarly, the effect of paste safflower phospholipid (PSP) which contains approximately 45% of neutral lipid was also compared to safflower oil (SO). Concentrations of total cholesterol in plasma and liver of rats fed the SP diet were markedly decreased in comparison with those of the other diets, but a slight reduction of total cholesterol in plasma and liver was observed in rats fed PSP diet. SP and PSP induced a reduction in the plasma level of low density lipoprotein (LDL) cholesterol as well as an increase in the level of high density lipoprotein (HDL) cholesterol. The activity of plasma lecithincholesterol acyltransferase (LCAT) was greatly increased in rats fed SP diet. These results suggest that the safflower phospholipids suppress the elevation of plasma and liver cholesterol and that this effect may depend on the phospholipid content in dietary lipid.

• 財団法人 学会誌刊行センターの論文

著者

• Furukawa Yuji

  Laboratory Of Nutrition Department Of Applied Biological Chemistry Faculty Of Agriculture Tohoku Uni

• Iwata Toshio

  Department Of Orthodontics School Of Dentistry Aichi-gakuin University

• Kimura Shuichi

  Laboratory Of Nutrition Faculty Of Agriculture Tohoku University

• TSUTSUMI Kentarou

  Department of Research and Development, The Rinoru Oil Mills Co., Ltd

• TSUTSUMI Kentarou

  Department of Research and Development, The Rinoru Oil Mills Co., Ltd.,

• HOSHI Seiko

  Laboratory of Nutrition Chemistry, Department of Food Chemistry, Faculty of Agriculture, Tohoku University

• KIMURA Shuichi

  Laboratory of Nutrition Chemistry, Department of Food Chemistry, Faculty of Agriculture, Tohoku University

• IWATA Toshio

  Department of Research and Development, The Rinoru Oil Mills Co., Ltd.,

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