下顎前歯部小臼歯部に発生したエナメル上皮線維腫の1例

概要

論文の詳細を見る
A 42-year-old woman presented with a hemispherical bony-hard nodule (size about 35×30 mm) in the muco-gingival area from the lower right first premolar to the left central incisor. X-ray examination showed a relatively clearly demarcated tumor mass, consisting of a mixture of tissue, which seemed to infiltrate the surrounding tissue in some areas. Biopsy was performed under the clinical diagnosis of a mandibular tumor, and the lesion was diagnosed to be an ameloblastic fibroma. Tumor extirpation and apicoectomy from the lower right first premolar to the left central incisor were performed. There were no distinct signs of a capsule and many microcysts were observed on the bone cavity surface after tumor excision. There has been no evidence of recurrence.<BR>Light microscopic examination revelaed proliferation of both epithelial and mesenchymal tissue in the excised tumor. In some large epithelial nests, columnar cells lined the periphery and loosely arranged cells resembling the stellate reticulum were in the central portion.<BR>Immunohistochemical properties were studied using a rabbit anti-mouse amelogenin antibody by ABC method. Collumnar cells forming the epithelial nest expressed a positive pattern. Tooth bud-like cells and cells resembling the stellate reticulum were not stained distinctly, and areas of hyalinization between epithelial and mesenchymal tissue were negative.
社団法人日本口腔外科学会の論文