Experimental study on free autograft of bisected lymph nodes. Electron microscopic research on the subcapsular sinus.:Electron microscopic research on the subcapsular sinus

スポンサーリンク

概要

論文の詳細を見る
Following right submandibular lymphadenectomy in Wistar rats, one of the bisected normal lymph nodes was autotransplanted to the vacant space from the left side without microvascular anastmosis.<BR>The transplants, especially in the subcapsular sinus, were examined for propriety of survival, phagocytosis and their ultrastructural restoration by transmission electron microscope.<BR>At four days and one week, a part of the transplants was nerotic and lymphoid cells had almost disappeared. But stromal cells, such as lymphendothelial cells including reticulum cells, remained and fundamental structures of the subcapsular sinus had been preserved.<BR>Restoration of the transplants began at one week, and fibrils, formed by lymphendothelial cells, were initially irregular in size but grew regular and lymphocytes increased in the subcapsular sinus with time. After four weeks, transplants demonstrated normal histology and function, and indicated no regressive degeneration even at twelve weeks. Lymphendothelial cells, characterized by plasmalemmal vesicles and intermediate junction like structure, did not show distinct phagocytosis in the normal condition. But they possesed many organella in cytoplasm and uptaken latex particles markedly in an active restoration process. Meanwhile, the lymph node does not reform after complete excision in the left side.<BR>The present study suggested that the free autotransplantation of bisected lymph node is an effective method for the reconstruction of lymph node function.
社団法人日本口腔外科学会の論文

著者

関連論文

スポンサーリンク