右側耳介下部に発生した石灰化上皮腫の1例

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A case of pilomatrixoma of the right subauricular region in a 23-year-old woman is reported along with the results of light microscopic (LM), scanning electron microscopic (SEM) and transmission electron microscopic (TEM) studies.<BR>A solitary circumscribed stone-hard subcutaneous nodule was noted in that area for about 13 years. Sialography showed no relationship between the tumor and parotid glands. An excisional tumor was covered with a thin capsule and carefully removed with surrounding tissue. The milkwhite colored tumor was hard, solid, and fragile. There has been no recurrence yet.<BR>LM examination revealed eosinophilic shadow cells and bone-like tissue without basophilic cells. The tumor was diagnosed as pilomatrixoma with ossification.<BR>SEM and TEM revealed shadow cells composed of thick bundles of fibrils. Nucleus and plasma membranes disappeared and cytoplasmic organella was absent. Shadow cells were oval in shape and arranged like paving stones. Branched fibrils took the place of plasma membranes, revealing variable width and arrangements. These characteristics of the tumor suggest a long clinical course of about 13 years.