米,リジン添加米飼料で生ずる肝脂質の蓄積に対する食物繊維の影響

概要

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In earlier studies total lipids and triglycerides were markedly increased in the liver of Sprague-Dawley rats fed a rice diet and in Donryu rats fed a rice diet supplemented with lysine. The study here was conducted to examine the effect of dietary fibers, such as cellulose, pectin, guar gum or konjac mannan, on the liver lipid accumulation of male Sprague-Dawley rats fed a rice diet and male Donryu rats fed a rice diet supplemented with 0.3% lysine-HCl. Each type of dietary fiber was added at 2% to the rice diet and at 5% to the rice diet supplemented with lysine. Rats were fed ad libitum for 21 or 30 days. The liver lipid content of Sprague-Dawley rats fed a rice diet with cellulose, pectin, guar gum or konjac mannan was significantly lower than in rats fed the same diet without dietary fiber. In Donryu rats fed a rice diet supplemented with lysine, the liver lipid content was significantly reduced by the addition of pectin, guar gum or konjac mannan, but not influenced by cellulose. The liver lipid reduction in rats receiving supplementary fiber was mainly due to a decrease in triglyceride. These results indicate that dietary fibers, such as pectin, guar gum or konjac mannan, depress liver lipid accumulation in both animal strains, but that the effect of cellulose differs between Sprague-Dawley and Donryu rats.