Spermatogenetic Activity after Early Postnatal Hypothalamic Lesion in Rats
スポンサーリンク
概要
- 論文の詳細を見る
Medio-basal hypothalamic lesions were made by electric coagulation in Sprague-Dawley strain rats 20-24 hours after birth. Testicular development in these animals was examined 20, 40 and 60-70 days after birth. Transection (Group 1) or severe lesion (Group 2) of the pituitary stalk caused arrest of both spermatogenesis and testicular development. In these animals, on the 40th and 60th day after birth, the seminiferous tubules were very small in diameter and no spermatids or spermatozoa were found in the lumen. The seminiferous epithelium was very thin, and spermatogenesis was arrested in the premeiotic stage. Lesion of the posterior part of the median eminence, including the stalk (Group 4), also induced testicular atrophy, but spermatogenesis was not disturbed. Damage of the anterior portion of the median eminence (Group 3) did not cause testicular atrophy. When the median eminence and the stalk were intact, lesions of the hypothalamus, including the subthalamus, mamillary body and half the hypothalamus (Group 5), did not depress spermatogenesis. The hypophysis did not show any degeneration in all cases examined, although the size was very small in Groups 1 and 2. These findings suggest that development of testiculotropic function of the hypophysis is dependent on the hypothalamus, especially on the posterior medio-basal hypothalamus, even though the hypophysis grows independently of hypothalamic control.
- 社団法人 日本内分泌学会の論文
著者
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Daikoku Shigeo
Department Of Anatomy School Of Medicine Tokushima University
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Shimizu Hiroshi
Department Of Animal Science Faculty Of Agriculture Hokkaido University
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OOKI TAKASHI
Department of Anatomy, School of Medicine, Tokushima University
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DAIKOKU SHIGEO
Departamento de Morfologia, Facultad de Medicina, Univercidad Nacional de Colombia
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DAIKOKU SHIGEO
Department of Anatomy, School of Medicine, Tokushima University
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SHIMIZU HIROSHI
Department of Anatomy, School of Medicine, Tokushima University
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