Effect of ACTH <I>in vivo</I> on the Phospholipid Exchange between Adrenal Microsomes and Mitochondria <I>in vitro</I>
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概要
- 論文の詳細を見る
Effect of ACTH administration on the rate of phospholipid exchange <I>in vitro</I> between rat adrenal microsomes and mitochondria was examined using <SUP>3</SUP>H-cholinelabeled adrenal microsomes as the donor of phospholipids. Increased rate of exchange was observed between control microsomes and mitochondria isolated from rats received 6 u. of ACTH 3.5 hr before death of the animals. On the contrary, mitochondria obtained from the animals treated with ACTH for consecutive 3 days exhibited less capacity of the exchange. The almost identical results were obtained when the microsomes obtained from ACTH-treated animals were used as the donor of phospholipids. Attempts for the exchange of phospholipid <I>in vitro</I> between inner and outer membranes of adrenal mitochondria and between microsomes and inner membrane of mitochondria were unsuccessful.
- 社団法人 日本内分泌学会の論文
著者
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ICHII SHOGO
Division of Physiology, Institute of Steroid Research and lst Department of Internal Medicine
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ICHII SHOGO
Division of Physiology and Pathology, National Institue of Radiological Sciences
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