Nuclei and DNA-Binding Form of the Steroid Receptor Complex in the Liver and the Ventral Prostate of Rats
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概要
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Repeated treatments of the liver cytosol prelabeled with <SUP>3</SUP>H-dexamethasone with DNA-cellulose followed by treatments with purified liver nuclei enabled us to assess the amount of two forms of dexamethasone-receptor complex, one binds only to nuclei and the other binds to DNA and nuclei. The comparable amount of these two forms of the receptor complex was detected in the dexamethasone-labeled liver cytosol, while only one form which binds only to nuclei was found in the liver cytosol labeled with antiglucocorticoid, cortexolone. The significant amount of receptor complex which binds to DNA and nuclei was not present in the cytosol from the ventral prostate preincubated with 3H-dihydrotestosterone.
- 社団法人 日本内分泌学会の論文
著者
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MURAKAMI Noriko
Division of Particle and Astrophysical Sciences, Graduate School of Science, Nagoya University
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ICHII SHOGO
Division of Physiology, Institute of Steroid Research and lst Department of Internal Medicine
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ICHII SHOGO
Division of Physiology and Pathology, National Institue of Radiological Sciences
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