Effect of ACTH on the Phosphorylation of Proteins in Subcellular Fractions of Rat Adrenal Glands
スポンサーリンク
概要
- 論文の詳細を見る
To elucidate the role of cAMP-dependent protein kinase in steroidogenic action of ACTH, effect of ACTH administration on the rate of protein phosphorylation in the adrenal subcellular fractions were examined by injecting <SUP>32</SUP>P-orthophosphate to rats 30 min before the death of animals. Bulk of the radioactivity was observed in the alkali-labile phosphorous from the nuclear fraction. Administration of ACTH caused a significant elevation in the radioactivity of the microsomal protein when compared on weight basis protein but the radioactivity in the other three fractions was not changed by the same treatment of animals. These results appeard to provide another evidence for that the site ACTH action mediated by cAMP is localized in microsomal fraction of rat adrenals.
- 社団法人 日本内分泌学会の論文
著者
-
MURAKAMI Noriko
Division of Particle and Astrophysical Sciences, Graduate School of Science, Nagoya University
-
ICHII SHOGO
Division of Physiology, Institute of Steroid Research and lst Department of Internal Medicine
-
ICHII SHOGO
Division of Physiology and Pathology, National Institue of Radiological Sciences
関連論文
- The Infrared Astronomical Mission AKARI
- Biopotency and Nuclear Binding in Glucocorticoids
- Binding Sites for Glucocorticoids in Cytosols from the Ventral Prostate and Seminal Vesicle of Rats
- Dynamics of Glucocorticoid Receptor and Induction of Tyrosine Aminotransferase in Rat Liver
- Rat Adrenal Corticosteroidogenesis; Effect of ACTH, Cycloheximide and Sterol Carrier Protein
- Effect of ACTH on the Phosphorylation of Proteins in Subcellular Fractions of Rat Adrenal Glands
- Studies on the Nuclear Binding of Steroid Hormone-Receptor Complex; Binding of Liver and Thymus Dexamethasone-Receptor Complex and Prostate Dihydrotestosterone-Receptor Complex to Nuclei from Various Tissues
- Studies on the Nuclear Binding of Steroid Hormone-Receptor Complex; Characteristics of Binding of Nuclei from Fetal Rat Liver to 3H-Dexamethasone-Liver Cytoplasmic Receptor Complex
- Nuclei and DNA-Binding Form of the Steroid Receptor Complex in the Liver and the Ventral Prostate of Rats
- Receptor Recycling: Liberation of Glucocorticoid Receptors from Liver Nuclei in vitro
- Effect of ACTH in vivo on the Phospholipid Exchange between Adrenal Microsomes and Mitochondria in vitro
- Further Studies on the Cytoplasmic 3H-Dexamethasone Receptor in the Liver from Adult and Fetal Rats
- Interaction of 3H-Dexamethasone-Receptor Complex with Nuclei: Inhibition by Ethidium Bromide
- Effect of Adrenalectomy and Gonadectomy on Protein Turnover of Liver, Kidney and Spleen of Mouse
- Effect of ACTH on Turnover of Phospholipids in Rat Adrenal Glands
- Short-and Long-Term Effect of ACTH in vivo on the Incorporation of 3H-Leucine into the Submitochondrial Fractions from Rat Adrenal Glands
- THE EFFECT OF AGE ON THE ACTIVITY OF CHOLESTEROL SIDE-CHAIN CLEAVAGE IN RAT TESTIS
- Nuclear Binding Sites in the Liver for Dexamethasone and in the Ventral Prostate for R1881
- Effect of Cortisol in vivo on Amino Acid Incorporation into Protein by Rat Liver Ribosomes in vitro
- Studies on Regenerating Adrenal Cortex 2. Autoradiographic and Electron Microscopic Observations
- Studies on Ribonucleic Acid Turnover in Rat Organs : Effects of Cortisol, Actinomycin D, and Cycloheximide
- Acute Effect of Corticotropin on the Incorporation of 3H-Choline into Phospholipid Faction of Subcellular Components from Rat Adrenal Glands
- Adenosine 3, 5-Monophosphate, Adenosine 3, 5-Monophosphate-Binding Protein and Protein Kinase in Rat Adrenal Glands; Fffect of Adrenocorticotrophin
- Effect of ACTH and Dexamethasone on the Rate of Protein and RNA Degradation in Rat Adrenal Glands
- Hormonal Regulation of Protein Synthesis in Rat Ventral Prostate
- ROLE OF PLASMA CHOLESTEROL IN RAT-ADRENAL CORTICOSTEROIDOGENESIS IN VITRO
- Effect of ACTH on the Interconversion of Ester and Free Cholesterol and Corticosterone Biosynthesis in Rat Adrenal Glands
- STUDIES ON REGENARATING ADRENAL CORTEX 1:STUDIES ON REGENARATING ADRENAL CORTEX 1 INCORPORATION OF 3H-THYMIDINE AND 3H-URIDINE, AND LEVELS OF ADRENAL ASCORBIC ACID, CHOLESTEROL, CHOLESTEROL SIDECHAIN-CLEAVING ACTIVITY,
- Effect of Sex Hormones on the Activity of Protein Kinases in Rat Ventral Prostate and Uterus
- Changes in the cytoplasmic androgen receptor of rat ventral prostate after administration of androgens, antiandrogens and anabolic steroids.