Conditions for Establishment of Reflex Ovulation in Light Estrous Rats
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概要
- 論文の詳細を見る
Continual anovulatory state associating with persistent vaginal cornification (light estrus) was induced by placing 4-day cycling rats under continuous lighting (LL). Uterine cervical stimulation was applied at arbitrary solar hours to light estrous rats showing continual vaginal estrus for more than 2 weeks. The ovulation was induced between 14 and 16hr after the stimulation dissociating entirely with solar hours. Injection of anti-LHRH serum 5min after the stimulation but not later than 20min blocked this ovulation. Ovulation thus induced was always followed by pseudopregnancy with continual leucocytic vaginal smear lasting 10.70 days. The change in concentrations of peripheral serum progesterone during this period was almost similar to that of normal pseudopregnancy except extremely low levels observed at the start and end.<BR>Effectiveness of the cervical stimulation for induction of ovulation in light estrous rats was related to not only the duration of light estrus but also the time after transfer to LL, suggesting that the neural mechanism of ovulation in light estrous rats shifted from that of the spontaneous to reflex ovulators due to the extinction of environmental photic cue.
- 社団法人 日本内分泌学会の論文
著者
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SUZUKI YOSHISUKE
Department of Veterinary Physiology, Faculty of Agriculture, University of Tokyo
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Murakami Noboru
Department Of Dermatology St. Marianna University School Of Medicine
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Takahashi Michio
Department Of Internal Medicine Kitasato University School Of Medicine
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Takahashi Michio
Department Of Civil Engineering College Of Engineering Nihon University
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SUZUKI YOSHISUKE
Department of Veterinary Physiology, Faculty of Agriculture University of Tokyo
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MURAKAMI NOBORU
Department of Veterinary Physiology, Faculty of Agriculture, University of Tokyo
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