ラット卵巣におけるインヒビンおよびアクチビンα,βAおよびβBサブユニットの局在〔英文〕
スポンサーリンク
概要
- 論文の詳細を見る
The localization of α, βA and βB subunits of inhibin/activin polypeptides was studied in the ovary and testis of sexually mature, immature, and embryonic rats. Specific staining with these three subunits was also evident in the oocytes from embryonic to mature female rats. This result suggests that inhibin- and activin-like substances may be produced in the oocytes and these substances may play a role in the oocyte growth and differentiation. Judging from the intensity of immunoreaction in mature female rats, the three subunits should be produced more abundantly in luteal cells than in the granulosa cells. Immunoreactive α, βA and βB subunits were observed in the cummulus oophorous in the morning (11:00), but not in the evening (23:00) on proestrus. The results are in well agreement with the previous report that inhibin α and βA subunit mRNA signals decline on proestrus evening. It is supposed that the cyclic change may be related with physiological phenomena prior to the ovulation, such as primary gonadotropin surges, loss of cummulus-oocyte gap junctions, or germinal vesicle breakdown. In both germ cells and Sertoli cells of the testis, α, βA and βB subunits were more abundant in the embryonic rat than in the mature rat. Although clear reactions with βA and βB subunits were detected in Leydig cells, α subunit was not detectable in the cells throughout the developmental stages examined.
- 社団法人日本獣医学会の論文
- 1991-04-15
著者
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HAYASHI Yoshihiro
Department of Pathology, Kochi Medical School, Kochi University
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OGAWA Kenji
Department of Surgery, Daini Hospital, Tokyo Women's Medical University
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Hayashi Y
Hadepartment Of Environmental Technology And Urban Planning Nagoya Institute Of Technology
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Hayashi Y
Univ. Tokyo Tokyo Jpn
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Shiota Kunio
Laboratory Of Cellular Biochemistry Veterinary Medical Science/animal Resource Science The Universit
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Shiota Kunio
Department Of Veterinary Physiology Veterinary Medical Science The University Of Tokyo
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Shiota Kunio
Department Of Veterinary Biochemistry Faculty Of Agriculture The University Of Tokyo
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KUROHMARU Masamichi
Department of Veterinary Anatomy, Graduate School of Agricultural and Life Sciences, The University
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Kurohmaru M
Univ. Tokyo Tokyo Jpn
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Kurohmaru Masamichi
Department Of Veterinary Anatomy Graduate School Of Agriculture And Life Sciences University Of Toky
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Kurohmaru Masamichi
Department Of Veterinary Anatomy Faculty Of Agriculture The University Of Tokyo
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TAKAHASHI Michio
Department of Veterinary Physiology, Veterinary Medical Science, The University of Tokyo
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Shiota K
Univ. Tokyo Tokyo Jpn
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Takahashi M
Univ. Tokyo Tokyo Jpn
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Nishida T
College Of Bioresource Sciences Nihon University
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Nishida Takao
Department Of Veterinary Anatomy Faculty Of Agriculture The University Of Tokyo
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Hayashi Yoshihiro
Department Of Pathology Kochi Medical School Kochi University
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Kurohmaru M
東京大学大学院農学生命科学研究科獣医解剖学
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Ogawa Kenji
Department Of Orthopaedic Surgery Faculty Of Medicine Saga University
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Ogawa K
Laboratory Animal Research Center The Institute Of Physical And Chemical Research (riken)
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Shiota K
Animal Resource Science/veterinary Medical Science University Of Tokyo
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Kurohmaru Masamichi
Department Of Veterinary Anatomy Graduate School Of Agricultural And Life Sciences The University Of
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Nishida Takao
Department Of Animal Science Nihon University
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Takahashi Michio
Department Of Internal Medicine Kitasato University School Of Medicine
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Takahashi Michio
Department Of Civil Engineering College Of Engineering Nihon University
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Ogawa Kenji
Department Of Applied Biological Chemistry Faculty Of Agriculture Shizuoka University
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Hayashi Yoshihiro
Department Of Micro System Engineering School Of Engineering Nagoya University
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Hayashi Yoshihiro
Department Of Gastroenterology Faculty Of Medicine Fukuoka University
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小川 健司
Department of Veterinary Anatomy, Faculty of Agriculture, The University of Tokyo
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HAYASHI Yoshihiro
Department of Veterinary Anatomy, Faculty of Agriculture, The University of Tokyo
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Kurohmaru Masamichi
Department of Veterinary Anatomy
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Shiota Kunio
Department of Cellular Biochemistry
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Hayashi Yoshihiro
Department of Applied Chemistry, Institute of Colloid and Interface Science, Science University of Tokyo
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TAKAHASHI MICHIO
Department of Chemical Engineering, University of Tokyo
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