Blockade of Ovulation in Rats by Forced Immobilization for Surgical Treatment
スポンサーリンク
概要
- 論文の詳細を見る
By using 4-day cycling rats, the influence of forced immobilization and a simplesurgical operation of cervical region, applied on the day of proestrus upon the expected ovulation on the following morning, were studied. When these treatments were given so as to cover the "critical period", the ovulation was effectively blocked and the complete blockade was established by the 4hr of forced immobilization alone, or the 2hr of that with the surgical operation, where the ovulation was delayed by one day and the vaginal diestrus lasted for 3days after the vaginal estrus of one day.<BR>Administration of rat hypothalamic extract or LH normalized the precipitation of the periodical ovulation in the rat, treated with the 2-hr immobilization and the surgical operation. The stimuli derived from these stressful treatments seemed to exert an inhibitory effect on LH-RF releasing mechanism to block the pre-ovulatory surge of LH and resulting in the delay in ovulation. Although a similar delay in ovulation was observed in pentobarbital anesthesia, its subsequence of the vaginal cytology was evidently different from that obtained in the stressful treatment. Different mechanisms would function in CNS, between the blockade response of the anesthesia and that of the forced immobilization with a surgical operation performed under arousal state.<BR>Only the ether inhalation among anesthetics used in unrestrained rats at the critical period had no effect on the periodical ovulation. It is noteworthy that the blockade of ovulation by the forced immobilization with a surgical operation can be prevented by the simultaneous application of ether anesthesia.
- 社団法人 日本内分泌学会の論文
著者
-
SUZUKI YOSHISUKE
Department of Veterinary Physiology, Faculty of Agriculture University of Tokyo
-
Yonetani Shinobu
Life Science Laboratories, Central Research Laboratories, Ajinomoto, Co., INC
-
JOJIMA MASAMITSU
Life Science Laboratories, Central Research Laboratories, Ajinomoto, Co., INC
関連論文
- Stimulatory Action of Ovine LH Releasing Factor on Synthesis of Luteinizing Hormone (LH) Demonstrated by the Rat Intratesticular Test System
- Rat Intratesticular Test Systems for Investigating Luteinizing Hormone Releasing Factor (LRF) and Luteinizing Hormone (LH) Activities : Activities: Effects of Rat Stalk-Median Eminence Extract and Internal Environment of Rat Testis upon Rat and Quail Ante
- Testicular Function of Actively Immunized Male Rats with LH Releasing Hormone (LHRH): A Possible Role of Prolactin on Regulation of Spermatogenesis
- Intratesticular Tissue Fluid (ITF) for the Micro-Bioassay of LH
- The Dependency of the Rat Estrous Cycle on the Daily Alternation of Light and Dark
- The Effect of the Uterine Cervical Stimulation at Postpartum Estrus upon the Post-weaning Fate of the Lactational Corpora Lutea
- Androgen Distribution in Male Rats
- Conditions for Establishment of Reflex Ovulation in Light Estrous Rats
- On Circulating Sex Steroids During the Estrous Cycle and the Early Pseudopregnancy in the Rat with Special Reference to its Luteal Activation
- Resumption of Cyclicity in Light Induced Persistent Estrus by Treatments with Serotonin or its Precursor
- Participation of Pregnant Uterus upon the Gestagen Secretion during Midpregnancy in the Rat
- Blockade of Ovulation in Rats by Forced Immobilization for Surgical Treatment
- LH Synthesizing Activity of Synthetic LH Releasing Hormone Assessed by Rat Pituitary Implanting System of Rat Intratesticular Test