シバヤギにおけるプロスタグランジンF2αの繰返し投与による不完全性周期の誘起
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概要
- 論文の詳細を見る
Follicular growth of ruminant species occurs more than once during an estrous cycle either resulting in ovulation (ovulatory follicular wave) or not resulting in ovulation (latent follicular wave). Using Shiba-goats, we examined if ovulation could be induced from every latent follicular wave and if the resulting ova were fertile. Ovarian follicular development was monitored daily by transrectal ultrasonographic examination in 20 female goats for 2 consecutive estrous cycles. After the second spontaneous ovulation (day 0 = ovulation), all animals were each treated with a luteolytic dose of prostaglandin F2α (PGF 2α) on days 3 and 4,which resulted in ovulation from the first latent wave. Fertile males goats (n=2) were immediately introduced to the first group of animals (n=5), resulting in 4 pregnancies. For the second group of goats (n=9), 4 consecutive short estrous cycles were induced by the PGF2 α treatment at a mean interval of 6.5 ± 1.2 days with a range of 4-9 days. Five of 9 goats were allowed to mate following 4 consecutive short ovulatory cycles; normal behavioral estrus was observed at each estrus, and four of five animals became pregnant. The third group of goats (n=6), in addition to PGF2α treatment, received exogenous progesterone supplement which allowed latent follicular development to occur, but prevented ovulation until the effect of progesterone supplement subsided. These results suggest that female Shiba-goats possess physiological mechanisms for the final steps of follicular maturation and subsequent ovulation at short intervals when progesterone production from the newly developed corpus luteum is terminated.
- 日本繁殖生物学会の論文
著者
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NISHIHARA Masugi
Department of Veterinary Physiology, Veterinary Medical Science, The University of Tokyo
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今川 和彦
東京大学大学院農学生命科学研究科動物育種繁殖学教室
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今川 和彦
東京大学 獣・動物育種
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LI Jun
Department of Orthopaedic Surgery, Emory University School of Medicine
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IMAKAWA Kazuhiko
Laboratory of Animal Breeding, Faculty of Agriculture, The University of Tokyo
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篠崎 和美
東京大学大学院農学生命科学研究科附属牧場
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Imakawa Kazuhiko
Laboratory Of Animal Breeding And Reproduction Department Of Veterinary Medical Sciences Graduate Sc
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李 俊佑
Department of Veterinary Physiology, Veterinary Medical Science, The University of Tokyo
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篠崎 和美
Experimental Station for Bio-Animal Science, Veterinary Medical Science, The University of Tokyo
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今川 和彦
Laboratory of Animal Breeding, Veterinary Medical Science, The University of Tokyo
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SAWASAKI Toru
Experimental Station for Bio-Animal Science, Veterinary Medical Science, The University of Tokyo
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TAKAHASHI Michio
Department of Veterinary Physiology, Veterinary Medical Science, The University of Tokyo
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Nishihara Masugi
Department Of Veterinary Physiology Graduate School Of Agricultural And Life Sciences The University
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SINOZAKI Kazumi
Experimental Station for Bio-Animal Science, Veterinary Medical Science, The University of Tokyo
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Li Jun
Department Of Biochemistry Zhongshan School Of Medicine Sun Yat-sen University
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Takahashi Michio
Department Of Civil Engineering College Of Engineering Nihon University
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