Synthesis and secretion of prolactin in the decidualized human endometrium unassociated with pregnancy in vitro.
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概要
- 論文の詳細を見る
The effect of the decidualization induced by the administration of sex steroid hormones on the human endometrial PRL contents and the mechanism of synthesis and secretion of PRL in this decidualized endometrium of non-pregnant women were investigated. The PRL contents increased in proportion to the degree of decidualization. <I>In vitro</I> secretion of PRL in decidualized human endometrium was inhibited by the protein synthesis inhibitors, while TRH, dopamine, and bromocriptine did not have any effects on PRL secretion in incubation experiments. These data suggest that the production and secretion of PRL in the human endometrium have no relation to the presence of conceptus, and furthermore, they are regulated by mechanism different from the pituitary PRL.
- 社団法人 日本内分泌学会の論文
著者
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Satoh Masahito
Department Of Cardiology Tachikawa General Hospital
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Taga Michiyoshi
Department Of Obstetrics And Gynecology Faculty Of Medicine University Of Tokyo Tokyo
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Minaguchi Hiroshi
Department Of Obstetrics And Gynecology Faculty Of Medicine University Of Tokyo Tokyo
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Mizuno Masahiko
Department Of Neurosurgery And Pediatrics Kansai Medical School
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Sakamoto Shoichi
Department Applied Physics Seikei University
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MINAGUCHI HIROSHI
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo
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SATOH MASAHITO
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo
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TAGA MICHIYOSHI
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo
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