Nuclear Concentration of <SUP>3</SUP>H-estradiol in Target Tissues of a Fetal Rat Demonstrated by Dry Mount Autoradiography
スポンサーリンク
概要
- 論文の詳細を見る
Distribution of radioactivity in various tissues has been studied by dry mount autoradiography after the injection of <SUP>3</SUP>H-estradiol in female fetal rats. <SUP>3</SUP>H-estradiol was found to be concentrated in nuclei of cells of the oviduct. Radioactivity is also concentrated in the cell nuclei of the ovary, suggesting some effect of estradiol on these nuclei of cells. In such non-target tissues, as intestine, kidney, lung, liver and muscle, no nuclear concentration of radioactivity was found and average silver grain density per 100μ<SUP>2</SUP> is much lower than that of the oviduct. Although, in the adrenal, radioactivity was found to be randomly distributed in cytoplasm as well as in nuclei, the average silver grain density per 100μ<SUP>2</SUP> in nuclei was relatively high compared to that of the other non-target organs. It seemed that the estrogen exerts some effect on the adrenal of a fetal rat.
- 社団法人 日本内分泌学会の論文
著者
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Nakai Toshiaki
Department Of Clinical Pathology University Of Tsukuba
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Sakamoto Shoichi
Department Of Applied Physics Seikei University
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KIGAWA Tomonori
Department of Obstetrics and Gynecology, Oita Medical College
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SHIGEMATSU AKIYO
Research Institute of Tuberculosis
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Kigawa Tomonori
Department Of Obstetrics And Gynecology Faculty Of Medicine University Of Tokyo Tokyo
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Sakamoto Shoichi
Department Applied Physics Seikei University
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SAKAMOTO SHOICHI
Department of Obstetrics and Gynecology, School of Medicine, University of Tokyo
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KIGAWA TOMONORI
Department of Obstetrics and Gynecology, School of Medicine, University of Tokyo
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NAKAI TOSHIAKI
Department of Obstetrics and Gynecology, School of Medicine, University of Tokyo
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NAKAI TOSHIAKI
Department of Clinical Pathology and Metabolism, Dokkyo University School of Medicine
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