Effect of concanavalin A on 5'-nucleotidase activity of rabbit blood platelets.
スポンサーリンク
概要
- 論文の詳細を見る
Ecto-5'-nucleotidase (ecto-5'-NU) of platelets was enhanced by concanavalin A (Con A). This effect of Con A was antagonized by α-methyl-D-mannose, a specific antagonist of Con A binding to glycoprotein. Coformycin, an adenosine deaminase inhibitor, did not change the effect of Con A on the ecto-5'-NU. Uptake of adenosine by platelets was not affected by Con A. It was suggested that the ecto-5'-NU of platelet might be a direct and primary site of action of Con A.
- 公益社団法人 日本薬理学会の論文
著者
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Nishio Hiroaki
Department Of Molecular Pharmacology Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama Univer
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Segawa Tomio
Department Of Pharmacology Institute Of Pharmaceutical Sciences Hiroshima University School Of Medic
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TAKESHITA Keiko
Department of Pharmacology, Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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OKUGAWA Kimiko
Department of Pharmacology, Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine
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