Effects of Antihypertensive Treatments on Ocular Lesions of Streptozotocin-Induced Diabetes Mellitus in Spontaneously Hypertensive Rats
スポンサーリンク
概要
- 論文の詳細を見る
Effects of antihypertensive treatments on ocular lesions were evaluated in spontaneously hypertensive (SHR) rats with streptozotocin (STZ)-induced diabetes mellitus. STZ treatment induced ocular lesions such as narrowing of retinal arterioles, caliber irregularity, papilledema and cataracta in these rats. Enalapril, ramipril and arotinolol decreased blood pressure (BP) and prevented the progress of ocular lesions. Nisoldipine tended to decrease blood glucose (BG) and prevented the progress of ocular lesions. Therefore, antihypertensive treatments were shown to be effective in preventing the progress of ocular lesions in hypertensive rats with diabetes mellitus. Hypertension, as well as high BG, was suggested to play an important role in inducing ocular lesions.
- International Heart Journal刊行会の論文
著者
-
Kishi Koichiro
Department Of Legal Medicine And Molecular Genetics Gunma University Graduate School Of Medicine
-
Shimizu Hiroyuki
Department Of Biochemistry And Molecular Biology Center For Advanced Medical Technology Nippon Medic
-
SOKABE Hirofumi
Departments of Pharmacology, Jichi Medical School
-
SOKABE Hirofumi
Departine rt of Pharmacology, Jichi Medical School
-
Kusaka Miho
Departments of Pharmacology, Jichi Medical School
-
Kusaka Miho
Department of Pharmacology, Jichi Medical School
-
Miyazawa Atsuko
Departments of Ophtalmology, Jichi Medical School
関連論文
- Usefulness of [^C]Methionine PET in the Diagnosis of Dysembryoplastic Neuroepithelial Tumor with Temporal Lobe Epilepsy
- Effects of Passive Smoking on Serum Levels of Carotenoids and α-Tocopherol
- Associations of Individuals' Health-related Behavior with Their Own or Their Spouses' Smoking Status
- Validation of Simplified Diet History Questionnaire
- Frequent Hard Physical Activity Lowered Serum β-Carotene Level in a Population Study of a Rural City of Japan
- Molecular epidemiology of enterovirus 71 infection in the Western Pacific Region
- Choice of Response Scale for Health Measurement : Comparison of 4, 5, and 7-point Scales and Visual Analog Scale
- Improved Method for the Component Sugar Analysis of Glycoproteins by Pyridylamino Sugars Purified with Immobilized Boronic Acid
- Disinfection Kinetics of Legionella pneumophila by Hydrogen Peroxide
- A Japanese Encephalitis Virus NS3 Inhibitor Produced by a Streptomyces sp.
- Molecular, Biochemical and Immunological Analyses of Canine Pancreatic DNase I
- Usefulness of deoxyribonuclease I (DNase I) polymorphism for individualization from small aged urine stains
- Carp Hepatopancreatic DNase I : Biochemical, Molecular, and Immunological Properties
- Production of murine monoclonal anti-human DNase II antibodies, and their use for immunoaffinity purification of DNase II from human liver and urine
- DNase I : structure, function, and use in medicine and forensic science
- Japanese population data for two STR loci, HumTPO and HumLPL
- Simultaneous typing of the STR loci, vWF and HumTPO, using discontinuous polyacrylamide gel electrophoresis
- Identification of the Three Non-identical Subunits Constituting Human Deoxyribonuclease II.
- Deoxyribonuclease I from Rat Urine: Affinity Purification, Characterization, and Immunochemical Studies
- Correlation of Alpha-1-Antitrypsin (PI) Polymorphism between Blood and Semen
- Surgical Indication for Refractory Childhood Epilepsy
- S-II-13. Nomal Pressura Hydrocephalus : Analysis of 12 cases
- Surgical treatment of early-infantile epileptic encephalopathy with suppression-bursts associated with focal cortical dysplasia
- Surgical Treatment of a Case of Early Infantile Epileptic Encephalopathy with Suppression-Bursts Associated with Focal Cortical Dysplasia
- Trends in Prevalence Rates of Asymptomatic Aortic Aneurysms in Japan Based on Autopsy Series
- Effects of Family-Togetherness on the Food Selection by Primary and Junior High School Students : Family-Togetherness Means Better Food
- Validation of Recalled Food Intake in the Past in a Japanese Population
- Laparoscopic Urological Surgery : Experience at Nippon Medical School
- Food Diversity and Validity of Semiquantitative Food Frequency Questionnaire
- Study on surgical treatment of intractable childhood epilepsy
- サルモネラのO抗原の遺伝的解析-4-サルモネラE群のO抗原1,3,19および34の遺伝〔英文〕
- サルモネラのO抗原の遺伝的解析-3-サルモネラE群のO抗原3,10および15の遺伝〔英文〕
- Effectiveness of Cerebral Hemispherotomy for Improving Behavioral Disorders Associated With Intractable Post-traumatic Seizures
- High-frequency (20MHz) endoluminal ultrasonography to assess the depth of invasion by superficial bladder tumors
- II D6 Usefulness of C11-methionine PET in the diagnosis of benign tumors presenting with temporal lobe epilepsy
- Administration time difference of candesartin effect on albuminuria in type 2 diabetic patients
- Contribution of Fasting and Postprandial Hyperglycemia to Hemoglobin A_ in Insulin-Treated Japanese Diabetic Patients
- Rapid Effect of nCPAP Therapy on Circulating Plasma Leptin in OSAS Patients
- Risk Factors for Lung Cancer among Northern Thai Women: Epidemiological, Nutritional, Serological, and Bacteriological Surveys of Residents in High- and Low-incidence Areas
- Suicide Gene Therapy for Chemically Induced Rat Bladder Tumor Entailing Instillation of Adenoviral Vectors
- Self-reported Diabetes Mellitus and Risk of Mortality from All Causes, Cardiovascular Disease, and Cancer in Takayama : A Population-based Prospective Cohort Study in Japan
- Rationality/Anti-emotionality Personality and Dietary Habits in a Community Population in Japan
- Prospective cohort study of body mass index in adolescence and death from stomach cancer in Japan
- Improved treatment results of non-Hodgkin's lymphoma in children: a report from the Children's Cancer and Leukemia Study Group of Japan
- Sleep spindles in human prefrontal cortex : an electrocorticographic study
- Startle Epilepsy with Infantile Hemiplegia: Report of Two Cases Improved by Surgery
- Prevalence of the myelodysplastic syndromes in Japan
- Ferroelectric Properties and Structure Distortion in A-Site-Modified SrBi_2Ta_2O_9
- Improvement of a multiplex PCR system for DYS441, DYS442, DYS443, DYS444 and DYS445, and a population study in 340 Japanese males
- Advanced carcinoma of the prostatic urethra in a patient with marked response to chemotherapy, leading to preservation of the bladder
- Job Stress, Social Support at Work, and Insomnia in Japanese Shift Workers
- III B4 TLE associated with atypical anterobasal temporal foci : diagnosis and surgical management
- Spontaneous Regression of a Primary Cerebral Tumor Following Vasospasm Caused by Subarachnoid Hemorrhage Due to Rupture of an Intracranial Aneurysm : Case Report
- Effect of Vitamin K_2 (Menaquinone-7) and Soybean Isoflavone Supplementation on Serum Undercarboxylated Osteocalcin in Female Long-Distance Runners
- Disturbed Spatial Learning of Rats After Intraventricular Administration of Transforming Growth Factor-β1
- Clinical applications of DNase I, a genetic marker already used for forensic identification
- HISTO-BLOOD GROUP LEWIS GENOTYPING FROM HUMAN HAIRS AND BLOOD
- Modified functional hemispherectomy in hemimegalencephaly
- Association between Birth Weight and Serum Lipid Concentration in Premenopausal Japanese Women
- Relations of Insulin Resistance and Serum Concentrations of Estradiol and Sex Hormone-binding Globulin to Potential Breast Cancer Risk Factors
- Theta oscillation in the human anterior cingulate cortex during all-night sleep : an electrocorticographic study
- Effect of extracorporeal shock waves on callus formation during bone lengthening
- The role of β-tricalcium phosphate in vascularized periosteum
- Effects of Menstrual and Reproductive Factors on the Risk of Breast Cancer : Meta-analysis of the Case-Control Studies in Japan
- A 30-year-old male treated by neurosurgery against temporal lobe epilepsy
- Nesfatin-1 : An Overview and Future Clinical Application
- Leptin Resistance and Obesity
- Factors Affecting Response to Mail Questionnaire : Research Topics, Questionnaire Length, and Non-response Bias
- Postoperative development of children after hemispherotomy
- Temporal Lobe Epilepsy Caused by Dermoid Cyst
- Pathological effect of seizures on the hippocampus in cases with temporal lobe epilepsy caused by brain tumors
- Presence of human herpesvirus 6 and herpes simplex virus detected by polymerase chain reaction in surgical tissue from temporal lobe epileptic patients
- Lateral Temporal Polar Approach to Mesial Temporal Lesions
- Interictal hyperperfusion observed in infants with cortical dysgenesis
- CHRONIC EFFECTS OF A β-ADRENOCEPTOR BLOCKING DRUG, 4-[3-(tert-BUTYLAMINO)-2-HYDROXYPROPOXY]-N-METHYLISOCARBOSTYRIL HYDROCHLORIDE (N-696), IN HYPERTENSIVE RATS
- CHRONIC EFFECTS OF AROTINOLOL (S-596) IN SPONTANEOUSLY HYPERTENSIVE RATS
- Correlation of bone status in mothers and daughters and the improvement of bone status
- RISK FACTORS FOR BREAST CANCER : FINDINGS FROM COMPARATIVE STUDIES ON JAPANESE IN JAPAN, JAPANESE AND WHITES IN THE UNITED STATES
- Nutrient Intakes in Relation to Style of Breakfast and Taste Preferences
- Outcome of Long-Term Vagus Nerve Stimulation for Intractable Epilepsy
- Coexistence of Ganglioglioma and Cortical Dysplasia in a Patient with Intractable Epilepsy : Case Report
- Identification, characterization and forensic application of novel Y-STRs
- A satiety molecule, Nesfatin-1 in the hypothalamus
- Surgical Outcome of Corpus Callosotomy in Patients with Drop Attacks
- Neuronal Disconnection for the Surgical Treatment of Pediatric Epilepsy
- Evaluation of Self-Organized Learning in a Neural Network by Means of Mutual Information
- Reliability and Validity of a Questionnaire for Assessment of Energy Expenditure and Physical Activity in Epidemiological Studies
- Foreword
- EFFECTS OF A COMBINED USE OF STEROIDAL AND NONSTEROIDAL ANTI-INFLAMMATORY DRUGS ON E. COLI ENDOTOXIN-INDUCED UVEITIS IN PIGMENTED RABBITS
- Cell proliferation in visceral organs induced by ventromedial hypothalamic (VMH) lesions : Development of electrical VMH lesions in mice and resulting pathophysiological profiles
- A novel 56-bp variable tandem repeat polymorphism in the human deoxyribonuclease I gene and its population data
- サルモネラG,RおよびU群での血流型活性抗原の遺伝 (サルモネラのO抗原の遺伝的解析-1,2-〔英文〕)
- Effects of Antihypertensive Treatments on Ocular Lesions of Streptozotocin-Induced Diabetes Mellitus in Spontaneously Hypertensive Rats
- Renal Lesions of Streptozotocin-Induced Diabetes Mellitus in Spontaneously Hypertensive Rats
- Glutamate-pyruvate transaminase (GPT) polymorphism detected in human urine by isoelectric focusing.
- .ALPHA.-L-fucosidase polymorphism in human urine revealed by isoelectric focusing.
- Specific antibody to the urine samples of human adult males.
- Structural and functional alterations of mesenteric vascular beds in spontaneously hypertensive rats.
- Molecular, Biochemical and Immunological Analyses of Canine Pancreatic DNase I
- Deoxyribonuclease I from Rat Urine: Affinity Purification, Characterization, and Immunochemical Studies.