Stereoselective Vinylogous Mukaiyama Aldol Reaction of α-Haloenals
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概要
- 論文の詳細を見る
We have developed a high-yielding and stereoselective vinylogous Mukaiyama aldol reaction (VMAR) of α-haloenals. Contrary to the simple α,β-unsaturated aldehyde, α-haloenals were found to be reactive affording the corresponding VMAR adducts in excellent yields. Some transformations of VMAR adducts by Pd-mediated cross-coupling were also examined in order to demonstrate the synthetic utility of VMAR of α-haloenals.
- 公益社団法人 日本薬学会の論文
著者
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Suzuki Takahiro
Faculty of Health Sciences, Department of Human Care Engineering, Nihon Fukushi University
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KOBAYASHI Susumu
Faculty of Pharmaceutical Sciences, Science University of Tokyo
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Kobayashi Susumu
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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NAKAZAKI Atsuo
Faculty of Pharmaceutical Sciences, Tokyo University of Science
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Nakazaki Atsuo
Faculty Of Pharmaceutical Sciences Tokyo University Of Science
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Iwasaki Yoichi
Faculty of Pharmaceutical Sciences, Tokyo University of Science
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Matsui Ryosuke
Faculty of Pharmaceutical Sciences, Tokyo University of Science
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Suzuki Takahiro
Faculty Of Health Sciences Department Of Human Care Engineering Nihon Fukushi University
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