Deprotection of the Methoxymethyl Group on 3-Spiro-2-oxindole under Basic Conditions
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概要
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Deprotection of a methoxymethyl (MOM) group on an oxindole nitrogen under basic conditions is demonstrated. The mechanisms of both the deprotection and the formation of N-methyloxindole were revealed by using deuterated NaOMe–MeOH in mechanistic studies.
著者
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Kobayashi Susumu
Faculty Of Pharmaceutical Sciences Science University Of Tokyo
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Nakazaki Atsuo
Faculty Of Pharmaceutical Sciences Tokyo University Of Science
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Suzuki Takahiro
Faculty Of Health Sciences Department Of Human Care Engineering Nihon Fukushi University
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Iwakiri Kanako
Faculty of Pharmaceutical Sciences, Tokyo University of Science
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Hirano Tomohiro
Faculty of Pharmaceutical Sciences, Tokyo University of Science
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