Therapy-related myelodysplastic syndrome following cyclophosphamide pulse and/or methotrexate therapy in a patient with systemic lupus erythematosus.
スポンサーリンク
概要
- 論文の詳細を見る
A 27-year-old woman exhibited progressive pancytopenia during cyclophosphamide pulse therapy for lupus nephritis and low-dose methotrexate therapy for severe arthralgia. Bone marrow aspiration revealed highly abnormal cell morphology, indicating therapy-related myelodysplastic syndrome. Pancytopenia and bone marrow cell morphology improved 3 months after discontinuation of cyclophosphamide. It is necessary to promptly examine bone marrow cell morphology and chromosomal aberration in cases with connective tissue diseases complicated by sudden cytopenia during immunosuppressive therapy with chemotherapeutic agents.
著者
-
Ikeda Kazuhiko
Department Of Cardiology And Hematology Fukushima Medical University
-
Ogawa Kazuei
Department Of Cardiology And Hematology Fukushima Medical University
-
Iwadate Haruyo
Department Of Gastroenterology And Rheumatology Fukushima Medical University School Of Medicine
-
Kobayashi Hiroko
Department Of Gastroenterology And Rheumatology Fukushima Medical University School Of Medicine
-
Watanabe Hiroshi
Department Of Applied Chemistry And Bioengineering Graduate School Of Engineering Osaka City Univers
-
Ohira Hiromasa
Department Of Gastroenterology And Rheumatology Fukushima Medical University
-
IKEDA KAZUHIKO
Department of Cardiology and Hematology, Fukushima Medical University School of Medicine
-
Yano Kiori
Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine
-
OHIRA HIROMASA
Department of Gastroenterology and Rheumatology
-
IWADATE HARUYO
Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine
-
KOBAYASHI HIROKO
Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine
-
Kobayashi Hiroko
Department of Cardiovascular Disease Research, Eisai Tsukuba Research Laboratories
関連論文
- Novel Preparation of Intercellular Lipid Models of the Stratum Corneum Containing Stereoactive Ceramide
- Hepatocellular Carcinoma with PIVKA-II Production in a Young Laboratory Monkey
- 凝固異常・消化器症状を呈した systemic mastocytosis
- 14) ICD植え込み後に自家末梢血幹細胞移植を施行し,心筋拡張障害の改善を確認し得た心アミロイドーシスの一例(第145回日本循環器学会東北地方会)
- Participation of mast cells in angiogenesis in the border zone of myocardial infarction in rats
- Attenuation of Diastolic Heart Failure and Life-Threatening Ventricular Tachyarrhythmia After Peripheral Blood Stem Cell Transplantation Combined With Cardioverter-Defibrillator Implantation in Myeloma-Associated Cardiac Amyloidosis
- A CASE OF STEROID-REFRACTORY ULCERATIVE COLITIS COMPLICATED WITH CYTOMEGALOVIRUS PNEUMONIA
- 心筋虚血に対する自己骨髄/末梢血幹細胞移植による血管新生療法の経験(日本循環器学会東北地方会第135回学術集会)
- BREAKTHROUGH OF IMMUNE SELF-TOLERANCE TO CALRETICULIN INDUCED BY CpG-OLIGODEOXYNUCLEOTIDES AS ADJUVANT
- INHIBITORY OLIGODEOXYNUCLEOTIDE IMPROVES GLOMERULONEPHRITIS AND PROLONGS SURVIVAL IN MRL-lpr/lpr MICE
- Role of CpG ODN in Concanavalin A-Induced Hepatitis in Mice
- Hepatocellular Carcinoma Associated with Wilson's Disease
- Endovascular Stent-Grafting for Recurrent Aneurysm in Behcets Disease
- Effectiveness of Intragastric Immunization with Protein and Oligodeoxynucleotides Containing a CpG Motif for Inducing a Gastrointestinal Mucosal Immune Response in Mice
- Heterotopic sebaceous glands in the esophagus : Histopathological and immunohistochemical study of a resected esophagus
- Solitary esophageal metastasis of breast cancer with 15 years' latency : A case report and review of the literature
- USEFULNESS OF COMPLEMENT SPLIT PRODUCT, Bb, AS A CLINICAL MARKER FOR DISEASE ACTIVITY OF LUPUS NEPHRITIS
- Low concentration of serum haptoglobin has impact on understanding complex pathophysiology in patients with acquired bone marrow failure syndromes
- NONINVASIVE MYOCARDIAL ENDOTHELIAL INTERVENTION IN THE PERSISTENCE OF CORONARY STENOSIS : A CONCEPT OF MYOCARDIAL ENDOTHELIAL NITRIC OXIDE ACTIVATOR THROUGH HEART FAILURE RESEARCH ON CLINICAL DEMAND
- 非心筋細胞の培養上清による心筋虚血・再灌流障害軽減効果(日本循環器学会東北地方会第135回学術集会)
- 47) ICD植え込み術を施行したアドリアマシン心筋障害の一例(日本循環器学会 第132回東北地方会)
- PE-150 Comparison of Dilated Cardiomyopathy and Coronary Artery Disease in Effectiveness of Dl-sotalol on the Recurrence of Ventricular Tachyarrhythmia(Arrhythmia, therapy-10 (A) PE25,Poster Session (English),The 70th Anniversary Annual Scientific Meeting
- Efficacy of Bepridil for Antiarrhythmic Drug Refractory Ventricular Tachyarrhythmias in ICD Patients with Structural Heart Disease(Arrhythmia, Pharmacological Therapy 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Possible Prevalence and Transmission of Acute Respiratory Tract Infections Caused by Streptococcus pneumoniae and Haemophilus influenzae among the Internally Displaced Persons in Tsunami Disaster Evacuation Camps of Sri Lanka
- RNA Editing and Short Variant of Serotonin 2C Receptor mRNA in Neuronally Differentiated NG108-15 Cells
- Antioxidant and Free Radical-Scavenging Activity of Choto-san and Its Related Constituents(Pharmacology)
- Chronic Treatment With Imipramine Inhibits Cell Growth and Enhances Serotonin 2C Receptor mRNA Expression in NG 108-15 Cells
- PJ-093 Extracellular but not Intracellular Acidosis Suppresses Endothelial Function by Inhibiting Intracellular Calcium Responses(Endothelium(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- IS121 Regulation of capacitative Ca^2+ influx in human monocytes/macrophages by myosin light-chain kinase
- Regulation of Bradykinin-Stimulated Cation Entry Into Endothelial Cells by tyrosine Kinase
- Excessive nitric oxide production and cardiac dysfunction in patients with chronic renal failure
- Microvascular Thrombosis in the Hepatic Vein of a Patient with Paroxysmal Nocturnal Hemoglobinuria
- P-Glycoprotein Mediates Efflux Transport of Darunavir in Human Intestinal Caco-2 and ABCB1 Gene-Transfected Renal LLC-PK1 Cell Lines
- PJ-566 Influence of CYP2C9 Genotype on Pharmacokinetics and Pharmacodynamics of Benzbromarone(Cardiovascular pharmacology, basic/clinical-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-561 Antiproliferative Effect of Cyclic AMP on Human Umbilical Vein Endothelial Cells through TGF-beta Inducing p21(Cip1/Waf1) Expression(Cardiovascular pharmacology, basic/clinical-6, The 71st Annual Scientific Meeting of the Japanese Circulation Socie
- Ulcerative Colitis Occurring in the Course of Rheumatoid Arthritis : A Case Successfully Treated with Mesalamine Enema
- Detection and Monitoring of Methotrexate-associated Lung Injury Using Serum Markers KL-6 and SP-D in Rheumatoid Arthritis
- Primary Sjogren's Syndrome Complicated by Sarcoidosis
- HEMATOPOIETIC STEM CELL TRANSPLANTATION IN THE DEPARTMENT OF HEMATOLOGY, FUKUSHIMA MEDICAL UNIVERSITY
- Transient Improvement of Left Ventricular Function After Peripheral Blood Stem Cell Transplantation in a Patient With Myelodysplastic Syndrome and Dilated Cardiomyopathy
- B-cell Chronic Lymphocytic Leukemia is Complicated by Autoimmune Hemolytic Anemia and Anti-phospholipid Syndrome
- Glial localization of four-repeat tau in atypical progressive supranuclear palsy
- Fine Structural and Morphometric Studies on Gastric Parietal Cells of Peptic Ulcer Patients after Long-Term Treatment with Omeprazole
- Primary Structure and Properties of Ribonuclease Bm2 (RNase Bm2) from Bryopsis maxima(Biochemistry)
- Amino Acid Sequence and Characterization of a Nuclease (Nuclease Le3) from Lentinus edodes(Biochemistry & Molecular Biology)
- Amino Acid Sequence of a Trypsin Inhibitor from a Spirometra(Spirometra erinaceieuropaei)
- Relationship to Two Ribonucleases with Molecular Masses of 45 kDa and 37 kDa from the Culture Medium of Lentinus edodes
- Amino Acid Sequence of a Nuclease (Nuclease Le1) from Lentinus edodes
- Amino Acid Sequence of an Unique Ribonuclease with a C-Terminus rich in O-Glycosylated Serine and Threonine from Culture Medium of Lentinus edodes
- Comparison of Base Specificity and Other Enzymatic Properties of Two Protozoan Ribonucleases from Physarum polycephalum and Dictyostelium discoideum
- Characterization and Primary Structure of a Base Non-Specific and Acid Ribonuclease from Dictyostelium discoideum
- Primary Structure of Base Non-specific and Acid Ribonuclease from Bullfrog (Rana catesbeiana)
- The Base Specificities of Tomato Ribonuclease (RNase LE) and Its Asp44 Mutant Enzyme Expressed from Yeast Cells
- Purification and Characterization of the 2nd 5'-Nucleotide-forming Nuclease from Lentinus edodes
- Detection of Borna disease virus genome in normal human brain tissue.
- Immunochemical and immunohistochemical localization of Bcl-x protein in the rat central nervous system
- Hemolytic Uremic Syndrome Associated with Shiga Toxin Producing Eschericia coli Infection in a Healthy Adult Woman
- PE-270 Hypercholesterolemia Attenuates Cardioprotective Effect of Postconditioning in Association with Endothelial Nitric Oxide Dysfunction in Rat Acute Myocardial Infarction(Myocardial ischemia-reperfusion, basic/clinical-4 (IHD) PE45,Poster Session (Eng
- A case of systemic lupus erythematosus complicated by pure red cell aplasia and idiopathic portal hypertension after thymectomy
- PJ-549 The Novel Substrate Which Derives From Cultured Fibroblasts Improves Diastolic Dysfunction and Attenuates Infarction via PKC and Mitochondrial KATP Pathway(Myocardial Ischemia-Reperfusion, Basic and Clinical 4 (M) : PJ92)(Poster Session (Japanese))
- CD5-Positve Diffuse Large B-Cell Lymphoma Presenting in Bone Marrow without Lymphadenopathy
- Induction of Apoptosis in Vivo and in Vitro in Hairy Cell Leukemia Treated by Deoxycoformycin
- Assessment of Cardiac Function after Bone Marrow Transplantation by Quantitative ECG-Gated SPECT
- Effect of Replacing the Aspartic Acid / Glutamic Acid Residues of Bullfrog Sialic Acid Binding Lectin with Asparagine / Glutamine and Arginine on the Inhibition of Cell Proliferation in Murine Leukemia P388 Cells
- A New Type of RNase T2 Ribonuclease in Two Basidiomycetes Fungi, Lentinus edodes and Irpex lacteus(Biochemistry & Molecular Biology)
- Transfusion-related Acute Lung Injury Following Allogeneic Bone Marrow Transplantation in a Patient with Acute Lymphoblastic Leukemia
- THE INHIBITORY EFFECT OF ENALAPRIL ON THE NEOINTIMAL FORMATION AFTER ARTERIAL INTIMAL INJURY VIA APOPTOSIS
- Coronary Angiogenesis in the Infarct Border Areas and Its Relevance to Ventricular Remodeling : a Role of Cardiac Mast Cells(Angiogenesis 4 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- IS061 Caspase Inhibition Attenuates Myocardial Reperfusion injury in Rats
- B-cell Chronic Lymphocytic Leukemia is Complicated by Autoimmune Hemolytic Anemia and Anti-phospholipid Syndrome
- Noninvasive myocardial endothelial intervention in the persistence of coronary stenosis: a concept of myocardial endothelial nitric oxide activator through heart failure research on clinical demand
- PE-470 Reduced cardioprotective effect of ischemic preconditioning in chronic ischemic hearts due to preceding coronary stenosis via impaired PKC-mitochondrial KATP pathway(Myocardial Ischemia-Reperfusion, Basic (M) : PE80)(Poster Session (English))
- IS021 Caspase-1 inhibition protects ischemic coronary endothelium and attenuates post-infarction remodeling in rats
- P1-05-4 大量ガンマグロブリン療法が有効であった心不全症合併Churg-Strauss症候群の一例(P1-05 自己免疫疾患2,ポスターセッション,第23回日本アレルギー学会春季臨床大会)
- A long-term remission of renal amyloidosis with nephrotic syndrome after autologous peripheral blood stem-cell transplantation
- Therapy-related myelodysplastic syndrome following cyclophosphamide pulse and/or methotrexate therapy in a patient with systemic lupus erythematosus.
- Primary Biliary Cirrhosis Complicated by Polymyositis and Pulmonary Hypertension
- Clinical features of liver dysfunction in collagen diseases
- Comparison of Long-Term Clinical Outcomes of CHOP Chemotherapy between Japanese Patients with Nodal Peripheral T-Cell Lymphomas and Those with Diffuse Large B-Cell Lymphoma in the Study Group of the Tohoku Hematology Forum
- Impaired regulatory T cell reconstitution in patients with acute graft-versus-host disease and cytomegalovirus infection after allogeneic bone marrow transplantation
- USEFULNESS OF INTRAOPERATIVE ESOPHAGOGASTRODUODENOSCOPY IN A PATIENT WITH LUPUS ENTERITIS
- SYNTHETIC OLIGODEOXYNUCLEOTIDES INDUCE GASTRITIS IN MICE
- DOPPLER SONOGRAPHIC ANALYSIS OF SYNOVIAL VASCULARIZATION IN A PATIENT WITH RHEUMATOID ARTHRITIS TREATED WITH LEUKOCYTAPHERESIS
- ATTENUATION OF ISCHEMIC MYOCARDIAL INJURY AND DYSFUNCTION BY CARDIAC FIBROBLAST-DERIVED FACTOR(S)
- Association of the toll-like receptor 9 gene polymorphisms with behcet's disease in a Japanese population
- Liver Dysfunction in Patients with Systemic Lupus Erythematosus
- Pulmonary Hypertension and Refractory Heart Failure in a Patient with Crow-Fukase (POEMS) Syndrome
- Serum L-ficolin levels in patients with systemic lupus erythematosus
- Inhibitory Effects of a Novel Antiplatelet Agent, E5510, on Collagen-Induced Platelet-Derived Growth Factor Release and Aggregation of Human Platelets In Vitro.
- NONINVASIVE MYOCARDIAL ENDOTHELIAL INTERVENTION IN THE PERSISTENCE OF CORONARY STENOSIS: A CONCEPT OF MYOCARDIAL ENDOTHELIAL NITRIC OXIDE ACTIVATOR THROUGH HEART FAILURE RESEARCH ON CLINICAL DEMAND
- IMMUNE THROMBOCYTOPENIA IN AN ELDERLY PATIENT TREATED SUCCESSFULLY BY PULSE THERAPY WITH CYCLOPHOSPHAMIDE
- USEFULNESS OF INTRAOPERATIVE ESOPHAGOGASTRO-DUODENOSCOPY IN A PATIENT WITH LUPUS ENTERITIS
- USEFULNESS OF COMPLEMENT SPLIT PRODUCT, Bb, AS A CLINICAL MARKER FOR DISEASE ACTIVITY OF LUPUS NEPHRITIS
- INHIBITORY OLIGODEOXYNUCLEOTIDE IMPROVES GLOMERULONEPHRITIS AND PROLONGS SURVIVAL IN MRL-lpr/lpr MICE
- A 22-YEAR-OLD WOMAN WITH FULMINANT CHLAMYDIA PNEUMONIAE PNEUMONIA
- EFFECTIVENESS OF INTRAGASTRIC IMMUNIZATION WITH PROTEIN AND OLIGODEOXYNUCLEOTIDES CONTAINING A CpG MOTIF FOR INDUCING A GASTROINTESTINAL MUCOSAL IMMUNE RESPONSE IN MICE
- ROLE OF CpG ODN IN CONCANAVALIN A-INDUCED HEPATITIS IN MICE
- A CASE OF STEROID-REFRACTORY ULCERATIVE COLITIS COMPLICATED WITH CYTOMEGALOVIRUS PNEUMONIA
- Spontaneous Regression of Diffuse Large B-Cell Lymphoma Harbouring Epstein-Barr Virus: A Case Report and Review of the Literature
- Biliary hamartomas (von Meyenburg complex) complicated with microscopic polyangiitis