Some Embryological Aspects of Cholinergic Innervation in the Cardiovascular System — A Close Association With the Subintestinal Circulatory Channel
スポンサーリンク
概要
- 論文の詳細を見る
A series of our studies on the dog venous system revealed that cholinergic excitatory innervation was localized in a group of veins: the portal, mesenteric, and hepatic veins and the middle segment of the inferior vena cava. Our studies on pharmacological responsiveness of dog veins also revealed that they could be divided into two groups: the visceral and somatic parts, and the cholinergic excitatory innervation localized to the visceral part. Considering these results and some relevant literature, a hypothesis is proposed on the classification of muscles of the cardiovascular system and some embryological aspects of the parasympathetic cholinergic innervation in the circulatory system are discussed. The embryonic circulatory system of vertebrates can be divided into two parts: somatic and visceral. The body of an embryo is regarded as a double tube and vessels of the visceral part and the heart belong to the inner tube. The muscle of these vessels and the heart are derived from visceral mesoderm, either the coelomic epithelium or mesenchymal cells, in common with muscle of the digestive tube; and thus the parasympathetic cholinergic nerves innervating the muscle of the digestive tube also distribute to these vessels and the heart. The heart and vascular muscles in the visceral part are structures developed early in the course of evolution in invertebrates. Their primary function is to propel the body fluid, and the chief structure containing them is the subintestinal circulatory channel (ventral aorta − heart − subintestinal vein). They exhibit spontaneous, rhythmic activity, showing characteristics of a single unit muscle, and receive parasympathetic cholinergic innervation. On the other hand, the vascular muscles in the somatic part are endothelium-associated muscles developed anew in the vertebrate; do not contract spontaneously, being classified as a multiunit muscle; and lack parasympathetic cholinergic innervation.
著者
-
SHIGEI Tatsuro
Department of Pharmacology, Nagoya University School of Medicine
-
Shigei T
Nagoya Univ. School Of Medicine Nagoya Jpn
-
Tsuru Hiromichi
Department Of Pharmacology Faculty Of Medicine Toho University
-
Ishikawa Naohisa
Department Of Pharmacology Aichi Medical University School Of Medicine
-
Ishikawa Naohisa
Department Of Pharmacology Nagoya University School Of Medicine
-
Tsuru H
Department Of Pharmacology Toho University School Of Medicine
-
Yoshioka Koichi
Graduate School Of Sport System Faculty Of Physical Education Kokushikan University
-
Yoshioka Koichi
Graduate School Of Emergency Medical System Kokushikan University
-
Tsuru Hiromichi
Department of Pharmacology, Toho University School of Medicine, Japan
-
Yoshioka Koichi
Graduate School of Sport System, Faculty of Physical Education, Kokushikan University, Japan
-
Ishikawa Naohisa
Department of Pharmacology, Aichi Medical University, Japan
-
Shigei Tatsuro
Department of Cell Pharmacology, Nagoya University Graduate School of Medicine
関連論文
- Effects of 1-O-hexyl-2,3,5-trimethylhydroquinone on carbon tetrachloride-induced hepatic cirrhosis in rats
- Current Perspective : Absence of Endothelium in Invertebrate Blood Vessels : Significance of Endothelium and Sympathetic Nerve/Medial Smooth Muscle in the Vertebrate Vascular System
- Effect of Hydrogen Peroxide on Guinea Pig Nasal Mucosa Vasculature
- Cold Exposure Enhances Nitroxidergic Nerve-Mediated Vasodilatation in Canine Nasal Mucosa
- Some Embryological Aspects of Cholinergic Innervation in the Cardiovascular System — A Close Association With the Subintestinal Circulatory Channel
- Epidemiologic Study of Shigella sonnei from Sequential Outbreaks and Sporadic Cases Ueing Different Typing Techniques
- Preface
- DIFFERENT MODES OF ACTION OF CLONIDINE ON ISOLATED CANINE VEINS
- INCIDENCE OF EPINEPHRINE-INDUCED PULMONARY EDEMA IN RABBITS AND ACCOMPANYING METABOLIC CHANGES
- Are Sodium-Dependent V_1 Receptors and Sympathetic Nerve Activations Involved in Regulation of Blood Pressure in Borderline-Hypertensive Hiroshima Rats?
- Enhanced expression of naofen in kidney of streptozotocin-induced diabetic rats : possible correlation to apoptosis of tubular epithelial cells
- A NEW METHOD FOR THE BIOLOGICAL ASSAY OF CARDIOTONIC STEROIDS BASED ON THE POTENTIATION OF POTASSIUM-CONTRACTURE OF THE FROG VENTRICULAR MUSCLE
- Some Embryological Aspects of Cholinergic Innervation in the Cardiovascular System-A Close Association With the Subintestinal Circulatory Channel
- GRAPHIC ANALYSIS OF SEROTONIN EFFECTS IN DOG HEART-LUNG PREPARATION
- EFFECT OF ADRENERGIC AGONISTS ON THE CYCLIC AMP LEVEL IN THE LIVER AND HEART FROM NORMAL AND HYPOTHYROID RATS
- POSSIBLE EMBRYOGENETICAL DIFFERENCES OF THE DOG VENOUS SYSTEM IN SENSITIVITY TO VASOACTIVE SUBSTANCES
- Contribution of Endogenous Vasopressin to Regional Hemodynamics in Borderline-Hypertensive Hirosima Rats
- Role of Perivascular Sympathetic Nerves and Regional Differences in the Features of Sympathetic Innervation of the Vascular System
- Effects of Exogenous [Arg^8]-Vasopressin on Borderline-Hypertensive Hiroshima Rats
- Endothelium-Independent Relaxant Effect of 5-Hydroxytryptamine (5-HT) on the Isolated Rabbit Facial Vein
- CARDIOTONIC ACTION OF RING A-MODIFIED CARDENOLIDES, WITH SPECIAL REFERENCE TO CLEAVAGE OF THE RING
- RESPONSIVENESS OF ISOLATED DOG VEINS TO BRADYKININ: DISTRIBUTION AND A POSSIBLE CORRELATION WITH GENESIS OF THE VENOUS SYSTEM
- The participation of adenosine receptors in the adenosine 5'-triphosphate-induced relaxation in the isolated rabbit corpus cavernosum penis
- STIMULANT ACTION OF METHOXAMINE IN THE ISOLATED ATRIA OF NORMAL AND 6-PROPYL-2-THIOURACIL-FED RATS
- EFFECT OF THYROID HORMONE ON CYCLIC AMP PHOSPHODIESTERASE IN RAT KIDNEY
- GRAPHICAL ANALYSIS OF DRUG EFFECTS IN THE DOG HEART-LUNG PREPARATION-WITH PARTICULAR REFERENCE TO THE PULMONARY CIRCULATION AND EFFECTS OF NOREPINEPHRINE AND 5-HYDROXYTRYPTAMINE
- Direct Recording of Cardiac Output- and Venous Return-Curves in the Dog Heart-Lung Preparation for a Graphical Analysis of the Effects of Cardioactive Drugs
- 1-B-01 Recovery Processes of the Lung Functions after Breath-Holding During Exercise(The Proceedings of the 19th Annual Meetings of Japan Society of Exercise and Sports Physiology August 25・26, (Tokushima))
- PARTICIPATION OF CATECHOLAMINE IN THE DIGITOXIGENIN-INDUCED CONTRACTION OF ISOLATED DOG VEINS
- Release of Sympathetic Neurotransmitter Evoked by Electrical Stimulation Is Increased in the Chronically Decentralized Artery.
- An extension of pA principle to the potentiation of drug effects, and its application to the biological assay of some anticholinesterases and cardenolides.
- FINE-STRUCTURAL CHANGES OF ALVEOLAR WALLS IN FIBRIN-INDUCED, SO-CALLED NEUROGEN IC PULMONARY EDEMA OF THE RAT: COMPARATIVE REPRESENTATION WITH ADRENALINE AND ANTU-INDUCED EDEMA
- Inhalation of carbon dioxide enhances the coronary vasodilating action of isosorbide dinitrate in the dog.
- CARDIAC ACTIVE STEROIDS AND THE SLOW MUSCLE FIBRE
- Distribution of cholinesterase in canine venous system.
- Effects of catecholamines on isolated canine facial veins.
- Heterogeneity of .BETA.-adrenoceptor in canine veins: Comparison among the facial, portal and saphenous veins.
- Time course of the development of pre- and postjunctional supersensitivity in the rabbit ear artery after decentralization.
- Relatively Immediate Relaxant Effects of Cholera Toxin on Isolated Rabbit Blood Vessels.
- Contribution of cardiopulmonary nerves and blood PaCO2 to the coronary flow in a dog heart-lung preparation.
- A Study on the Protective Effect of Bromelain, Crude Pineapple Proteases, against Adrenaline Pulmonary Edema in Rats
- S1-receptor participation in serotonin-induced pulmonary edema in the dog.
- Evidence for the Excitatory Cholinergic Innervation in the Rabbit Portal Vein.
- Heterogeneity in vasorelaxant effects of .ALPHA.-human atrial natriuretic polypeptide in the dog.
- Factors influencing fibrin-induced pulmonary edema.
- A regional difference in endothelium-dependent relaxation responses to acetylcholine in the canine venous system.
- Role of naofen in apoptosis of hepatocytes induced by lipopolysaccharide through mitochondrial signaling in rats