Latent Hypoparathyroidism in an Osteoporotic Patient with Multiple Endocrinopathies and Secondary Hemochromatosis due to Multiple Blood Transfusions, Unmasked by Alendronate and Glucocorticoid at Adrenal Crisis
スポンサーリンク
概要
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A 30-year-old normocalcemic man with hypopituitarism, hypogonadism, diabetes mellitus, and secondary hemochromatosis due to multiple blood transfusions was admitted because of adrenal crisis. After intravenous administration of saline and cortisol, the corrected serum level of calcium decreased to 7.3 mg/dl. This osteoporotic patient had been prescribed alendronate for radial bone fracture. Since the increase in intact PTH (68 pg/ml) was impaired compared to that seen in hypocalcemic patients with secondary hyperparathyroidism, we presume that the patient has had latent hypoparathyroidism, which was unmasked by the administration of glucocorticoid and bisphosphonate. With a supplemented dose of 1α-OHD3, the patient has been eucalcemic.
著者
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Takano Kazue
Department Of Endocrinology Clinical Institute Of Endocrinology Tokyo Women's Medical Universit
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Sata Akira
Department Of Medicine Institute Of Clinical Endocrinology Tokyo Women's Medical University
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Harada Chie
Department Of Medicine Institute Of Clinical Endocrinology Tokyo Women's Medical University
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Hashimoto Etsuko
Department Of Internal Medicine And Gastroenterology Tokyo Women's Medical University
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Sato Kanji
Department Of Medicine Institute Of Clinical Endocrinology Tokyo Women's Medical College
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Tsuiki Mika
Department Of Medicine Institute Of Clinical Endocrinology Tokyo Women's Medical University
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Ohwada Rina
Department Of Medicine Institute Of Clinical Endocrinology Tokyo Women's Medical University
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Tanimoto Keiji
Department Of Anesthesia Kyoto University Hospital
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Saito Hiroshi
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Yamamoto Masaaki
Department Of Dermatology Hyogo College Of Medicine
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Okubo Yumiko
Department Of Medical Education Tokyo Women's Medical University
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Ohwada Rina
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University
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TAKANO KAZUE
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University
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Hashimoto Etsuko
Department of Medicine, Institute of Gastroenterology, Tokyo Women's Medical University
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Nishikawa Aiko
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University
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Yamamoto Masaaki
Department of Chemistry, Faculty of Science, Kanazawa University
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Saito Hiroshi
Department of Applied Chemistry, Graduate School of Engineering, Tohoku University
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Nishikawa Aiko
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University
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