1A2-E04 細胞ビルドアップ型ウェットナノロボティクスの機能創発 : 心筋細胞ゲルを用いた心筋細胞の3次元構築によるクラゲ型バイオマイクロマシンの構築と推進機構の創発(ナノ・マイクロバイオシステム)

概要

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In this study, we proposed a novel three dimensional tissue constructing method using shrinkage of cardiomyocyte gel toward the development of deformable bio-robot. The gel shtinkage effected by cell distribution and its traction force is attributed to nutrient distribution. We forcused on this mechanism and design the nuturient distribution to deform the gel to jellyfish-shaped structure. Finally we succeeded in constructing jellyfish-shaped structure and developing its moving function. Moreover we control the pulsation frequency of the structure with the drag stimulation. Since the velocity of moving has correlation with the pulsation frequency, it is possible to control the moving speed.
一般社団法人日本機械学会の論文
2011-05-26