DNA分子の非接触マニピュレーションに関する研究 : 第1報,誘電泳動力によるDNA分子の搬送

概要

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In this paper, we propose a new approach to noncontact manipulation of DNA molecules by dielectrophoretic force using the idea of a Micro DNA Flow System. Such systems can be constructed by using microfabrication technology. First, we designed a simple microelectrode-flow system and carried out experiments. Experimental demonstration of DNA transportation using dielectrophoretic force and direct observation of the DNA molecule in a nonuniform electric field was carried out using fluorescence microscopy. Motion of the DNA molecule is modeled in terms of the electric field generated by the electrode design. We compared the motion of the DNA molecule which is theoretically predicted with the experimental results. We demonstrated a simple electrode design and the possibility of transportation of DNA molecules based on the Micro DNA Flow System.
社団法人日本機械学会の論文
1996-07-25