2P2-J20 昆虫背脈管組織を用いたバイオアクチュエータの温度依存性の評価(ナノ・マイクロバイオシステム)

概要

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Living muscle cells have been attracted much interest as a novel actuator because they have high energy-conversion efficiency and can work only with chemical energy in glucose. Bioactuators using mammalian muscle tissues and cells were reported so far, however they require precise environmental control to keep them alive. We already proposed and demonstrated to utilize an insect dorsal vessel (heart muscle) tissue as an environmentally robust bioactuator. The actuator worked for more than 90 days at 25℃ without any maintenance. In this paper, the temperature dependence of the actuator was evaluated. The actuator was able to work at 5 to 40℃, but it was damaged irreversibly at 40℃. The Q10 (temperature coefficient from 20 to 30℃) of contraction frequency, force, and rate was 1.70, 0.77, and 1.28 respectively. These results suggest that the dorsal vessel is a less temperature-dependent bioactuator compared with mammalian cells.
一般社団法人日本機械学会の論文
2008-06-06